Toxin-mediated infectious botulism
Synonyms: Toxin-mediated infective botulism
- Type
- Clinical subtype
- Group
- Subtype of disorder
- Age of onset
- All ages
- Status
- active
Infectious botulism is a form of botulism, a rare acquired neuromuscular junction disease, characterized by descending flaccid paralysis caused by botulinum neurotoxins (BoNTs), produced <i>in vivo</i> leading to toxin-mediated infection. Infectious botulism includes wound botulism and intestinal toxemia botulism (infant botulism and adult intestinal botulism).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Toxin-mediated infectious botulism | Toxin-mediated infective botulism |
| fr | Botulisme toxi-infectieux | Botulisme par toxi-infection · Toxi-infection botulinique · Toxi-infection botulique |
| de | Botulismus, infektiöser | |
| es | Botulismo infeccioso por toxinas | |
| it | Botulismo infettivo tossina-mediato | |
| nl | Toxinegemedieerd infectieus botulisme | |
| pt | Botulismo infecioso | |
| pl | Botulizm zakaźny wywołany przez toksyny | = en |
| cs | Infekční botulismus zprostředkovaný toxinem | = en |
| uk | Інфекційний ботулізм, опосередкований токсином | Інфекційний ботулізм, опосередкований токсином |
| zh | 毒素介导的传染性肉毒中毒 | 毒素介导的传染性肉毒中毒 |
| tr | Toksin-aracılı bulaşıcı botulizm | Toksin aracılı enfektif botulizm |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A05.1 | NTBT | attributed | validated |
| ICD-11 | 1A11.1 | NTBT | index | validated |
| MONDO | 0016468 | E | validated | |
| UMLS | C5679843 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:1267Botulism
rare neurological diseases; rare ophthalmic disorders; rare infectious diseases
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
12 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0100021 | Cerebral palsy | |
| HP:0002019 | Constipation | |
| HP:0006824 | Cranial nerve paralysis | |
| HP:0006597 | Diaphragmatic paralysis | |
| HP:0001324 | Muscle weakness | |
| HP:0011499 | Mydriasis | |
| HP:0003470 | Paralysis | |
| Frequent (79-30%) | ||
| HP:0000651 | Diplopia | |
| HP:0002015 | Dysphagia | |
| HP:0002094 | Dyspnea | |
| HP:0000508 | Ptosis | |
| HP:0002747 | Respiratory insufficiency due to muscle weakness | |
Run the differential on the 7 obligate / very frequent terms
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/230800
- This record as JSON: /data/d/230800.json