Lassa fever
Synonyms: LF · Lassa hemorrhagic fever
- Type
- Disease
- Group
- Disorder
- Age of onset
- All ages
- Status
- active
Lassa fever (LF) is a potentially severe viral hemorrhagic disease caused by Lassa virus and characterized by initial fever and malaise followed by gastrointestinal symptoms and, in severe cases, bleeding, shock and multi-organ system failure.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Lassa fever | LF · Lassa hemorrhagic fever |
| fr | Fièvre de Lassa | Fièvre hémorragique de Lassa |
| de | Lassa-Fieber | LF · Lassa hämorrhagisches Fieber |
| es | Fiebre de Lassa | Fiebre hemorrágica de Lassa · LF |
| it | Febbre di Lassa | Febbre emorragica di Lassa · LF |
| nl | Lassa-koorts | LF · Lassa hermorragische koorts |
| pt | Febre de Lassa | |
| pl | Gorączka Lassa | Gorączka krwotoczna Lassa · LF |
| cs | Horečka Lassa | LF · Lassa hemoragická horečka |
| uk | Лихоманка Ласса | Геморагічна лихоманка Ласса · LF |
| zh | 拉沙热 | 拉沙出血热 |
| tr | Lassa ateşi | LF · Lassa hemorajik ateşi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A96.2 | E | specific | validated |
| ICD-11 | 1D61.2 | E | specific | validated |
| MONDO | 0005820 | E | validated | |
| MeSH | D007835 | E | validated | |
| UMLS | C0023092 | E | validated | |
| MedDRA | 10023927 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:341Viral hemorrhagic fever
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
| Point prevalence | <1 / 1 000 000 | — | Europe | Class only | Validated | European Medicines Agency 2018[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
28 annotations · validated 2021-08-30| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0025406 | Asthenia | |
| HP:0001945 | Fever | |
| HP:0003496 | Increased circulating IgM level | Diagnostic criterion |
| HP:0400008 | Menometrorrhagia | |
| HP:0005268 | Spontaneous abortion | |
| HP:0020071 | Viremia | |
| Frequent (79-30%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0100749 | Chest pain | |
| HP:0012735 | Cough | |
| HP:0002015 | Dysphagia | |
| HP:0002315 | Headache | |
| HP:0001324 | Muscle weakness | |
| HP:0002017 | Nausea and vomiting | |
| HP:0025439 | Pharyngitis | |
| Occasional (29-5%) | ||
| HP:0001892 | Abnormal bleeding | |
| HP:0002829 | Arthralgia | |
| HP:0003418 | Back pain | |
| HP:0000509 | Conjunctivitis | |
| HP:0002014 | Diarrhea | |
| HP:0002094 | Dyspnea | |
| HP:0000282 | Facial edema | |
| HP:0000365 | Hearing impairment | |
| HP:0000952 | Jaundice | |
| HP:0100520 | Oliguria | |
| HP:0001622 | Premature birth | |
| HP:0001250 | Seizure | |
| HP:0100806 | Sepsis | |
| HP:0031273 | Shock | |
Run the differential on the 6 obligate / very frequent terms
Annotation source: 28701331[PMID]_32125412[PMID]_31518896[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/99824
- This record as JSON: /data/d/99824.json