raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:70482

Carcinoma of esophagus

Synonyms: Esophageal carcinoma

Type
Clinical group
Group
Group of disorders
Age of onset
Adult
Status
active

Esophageal carcinoma (EC) is a tumor arising in the epithelial cells lining the esophagus and can be divided into two subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC).

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enCarcinoma of esophagusEsophageal carcinoma
frCarcinome de l'oesophage
deSpeiseröhrenkrebsÖsophaguskarzinom
esCarcinoma de esófagoCarcinoma esofágico · Cáncer esofágico
itCarcinoma dell'esofagoCarcinoma esofageo
nlCarcinoom van oesofagusCarcinoom van slokdarm · Oesofageaal carcinoom
ptCarcinoma do esófagoCarcinoma esofágico
plRak przełyku= en
csKarcinom jícnuEzofageální karcinom
ukКарцинома стравоходуКарцинома стравоходу
zh食管癌食管癌
trÖzofagus karsinomuÖzofageal karsinomu

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
MONDO0019086Evalidated
MONDO19086Evalidated
UMLSC0152018Evalidated
GARD6383Evalidated
MedDRA10030155Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

Children (4):

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

38 records
TypeClassValueAreaQualificationValidationSource
Annual incidence1-9 / 100 0007 / 100 000WorldwideValue and classValidatedWorld Health Organization 2008[OTHER]
Point prevalence1-9 / 100 0007.1 / 100 000EuropeValue and classValidatedWorld Health Organization 2008[OTHER]
Annual incidence1-9 / 100 0006.67 / 100 000EuropeValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Lifetime Prevalence1-5 / 10 00012.2 / 100 000EuropeValue and classValidated22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER]_[EXPERT]
Annual incidence1-9 / 100 0005.5 / 100 000United StatesValue and classValidatedNational Cancer OTHERitute 2012[OTHER]
Point prevalence1-9 / 100 0009.8 / 100 000WorldwideValue and classValidatedWorld Health Organization 2008[OTHER]
Annual incidence1-9 / 100 0006.873 / 100 000FranceValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-5 / 10 00010.82 / 100 000United KingdomValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.9 / 100 000IndiaValue and classValidatedWorld Health Organization 2008[OTHER]
Annual incidence1-5 / 10 00020 / 100 000ChinaValue and classValidatedWorld Health Organization 2008[OTHER]
Annual incidence1-9 / 100 0002.3 / 100 000AfricaValue and classValidatedWorld Health Organization 2008[OTHER]
Annual incidence1-9 / 100 0009 / 100 000JapanValue and classValidatedISBN:443075956[OTHER]_14530066[PMID]
Annual incidence1-9 / 100 0003.9 / 100 000CanadaValue and classNot yet validated23061066[PMID]
Annual incidence1-9 / 100 0008 / 100 000Russian FederationValue and classValidatedISBN:443075956[OTHER]_14530066[PMID]
Annual incidence1-5 / 10 00013 / 100 000Latin AmericaValue and classValidatedISBN:443075956[OTHER]_14530066[PMID]
Point prevalence1-9 / 1 000 0000.34 / 100 000Iran, Islamic Republic ofValue and classValidated23120941[PMID]
Annual incidence1-9 / 100 0003.293 / 100 000AustriaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0007.892 / 100 000BelgiumValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0001.194 / 100 000BulgariaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.281 / 100 000CroatiaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.718 / 100 000Czech RepublicValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.473 / 100 000EstoniaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.83 / 100 000FinlandValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0005.854 / 100 000GermanyValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0004.772 / 100 000IcelandValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0007.2 / 100 000IrelandValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.612 / 100 000ItalyValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.372 / 100 000LatviaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.468 / 100 000LithuaniaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0002.575 / 100 000MaltaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.592 / 100 000NorwayValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0002.414 / 100 000PolandValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0004.592 / 100 000PortugalValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0004.54 / 100 000SlovakiaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0003.904 / 100 000SloveniaValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0004.777 / 100 000SpainValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0006.413 / 100 000SwitzerlandValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]
Annual incidence1-9 / 100 0008.362 / 100 000NetherlandsValue and classValidatedRARECARE surveillance of rare cancers in Europe[OTHER]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

7

Sources for this card