{"orpha":70482,"name":"Carcinoma of esophagus","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["Esophageal carcinoma"],"definition":"Esophageal carcinoma (EC) is a tumor arising in the epithelial cells lining the esophagus and can be divided into two subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-70482/","orphanet_url":"https://www.orpha.net/en/disease/detail/70482","names":{"fr":{"name":"Carcinome de l'oesophage","definition":"Le carcinome de l'oesophage (CO) est une tumeur résultant des cellules épithéliales qui tapissent l'oesophage et peut être divisé en deux sous-types : le carcinome épidermoïde de l'oesophage et l'adénocarcinome de l'oesophage."},"de":{"name":"Speiseröhrenkrebs","synonyms":["Ösophaguskarzinom"],"definition":"Der Speiseröhrenkrebs (EC) ist ein Tumor, der im Epithel, das die Speiseröhre auskleidet, entsteht und der in zwei Subtypen unterteilt wird: Ösophagus-Plattenepithelkarzimon (ESCC) und -Adenokarzinom (EAC) (siehe jeweils dort)."},"es":{"name":"Carcinoma de esófago","synonyms":["Carcinoma esofágico","Cáncer esofágico"],"definition":"El carcinoma esofágico (CE) es un tumor que surge en las células epiteliales que recubren el esófago y puede dividirse en dos subtipos: carcinoma escamoso de esófago (CEE) y adenocarcinoma de esófago (ACE) (consulte estos términos)."},"it":{"name":"Carcinoma dell'esofago","synonyms":["Carcinoma esofageo"],"definition":"Il carcinoma dell'esofago (EC) è un tumore maligno che origina dalle cellule epiteliali che rivestono l'esofago e può essere distinto in due sottotipi: il carcinoma esofageo a cellule squamose (ESCC) e l'adenocarcinoma esofageo (EAC; si vedano questi termini)."},"nl":{"name":"Carcinoom van oesofagus","synonyms":["Carcinoom van slokdarm","Oesofageaal carcinoom"],"definition":"Oesofageaal carcinoom (EC) is een tumor die ontstaat in de epitheelcellen die de oesofagus bekleden, en kan ingedeeld worden in twee subtypes: oesofageaal plaveiselcelcarcinoom (ESCC) en oesofageaal adenocarcinoom (EAC)."},"pt":{"name":"Carcinoma do esófago","synonyms":["Carcinoma esofágico"]},"pl":{"name":"Rak przełyku","synonyms":["Esophageal carcinoma"]},"cs":{"name":"Karcinom jícnu","synonyms":["Ezofageální karcinom"]},"uk":{"name":"Карцинома стравоходу","synonyms":["Карцинома стравоходу"],"definition":"Esophageal carcinoma (EC) is a tumor arising in the epithelial cells lining the esophagus and can be divided into two subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC)."},"zh":{"name":"食管癌","synonyms":["食管癌"]},"tr":{"name":"Özofagus karsinomu","synonyms":["Özofageal karsinomu"]}},"xrefs":[{"source":"MONDO","code":"0019086","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"19086","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0152018","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"6383","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10030155","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":180821,"name":"Rare gastroesophageal tumor","classifications":[152,202]}],"children":[{"orpha":99976,"name":"Adenocarcinoma of the oesophagus and oesophagogastric junction","type":"Disease"},{"orpha":418945,"name":"Carcinoma of esophagus, salivary gland type","type":"Disease"},{"orpha":99977,"name":"Squamous cell carcinoma of the esophagus","type":"Disease"},{"orpha":418951,"name":"Undifferentiated carcinoma of esophagus","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":7.0,"area":"Worldwide","status":"Validated","source":"World Health Organization 2008[OTHER]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":7.1,"area":"Europe","status":"Validated","source":"World Health Organization 2008[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":6.67,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Lifetime Prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":12.2,"area":"Europe","status":"Validated","source":"22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER]_[EXPERT]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":5.5,"area":"United States","status":"Validated","source":"National Cancer OTHERitute 2012[OTHER]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":9.8,"area":"Worldwide","status":"Validated","source":"World Health Organization 2008[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":6.873,"area":"France","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":10.82,"area":"United Kingdom","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.9,"area":"India","status":"Validated","source":"World Health Organization 2008[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":20.0,"area":"China","status":"Validated","source":"World Health Organization 2008[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":2.3,"area":"Africa","status":"Validated","source":"World Health Organization 2008[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":9.0,"area":"Japan","status":"Validated","source":"ISBN:443075956[OTHER]_14530066[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.9,"area":"Canada","status":"Not yet validated","source":"23061066[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":8.0,"area":"Russian Federation","status":"Validated","source":"ISBN:443075956[OTHER]_14530066[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":13.0,"area":"Latin America","status":"Validated","source":"ISBN:443075956[OTHER]_14530066[PMID]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.34,"area":"Iran, Islamic Republic of","status":"Validated","source":"23120941[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.293,"area":"Austria","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":7.892,"area":"Belgium","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.194,"area":"Bulgaria","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.281,"area":"Croatia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.718,"area":"Czech Republic","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.473,"area":"Estonia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.83,"area":"Finland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":5.854,"area":"Germany","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":4.772,"area":"Iceland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":7.2,"area":"Ireland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.612,"area":"Italy","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.372,"area":"Latvia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.468,"area":"Lithuania","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":2.575,"area":"Malta","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.592,"area":"Norway","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":2.414,"area":"Poland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":4.592,"area":"Portugal","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":4.54,"area":"Slovakia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.904,"area":"Slovenia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":4.777,"area":"Spain","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":6.413,"area":"Switzerland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":8.362,"area":"Netherlands","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":null}