raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:440368

Necrotizing soft tissue infection

Synonyms: NSTI

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare infectious disease characterized by painful, rapidly progressive infection of deep soft tissue structures. Infections can be mono- or polymicrobial and involve gram-positive cocci, enteric gram-negative bacilli, anaerobes, among others. Fungal infections have also been described in rare cases. Physical examination findings are often subtle and may include erythema, bullae, induration of subcutaneous tissues, and tenderness to palpation.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enNecrotizing soft tissue infectionNSTI
frInfection nécrosante des tissus mous= en
deNekrotisierende Weichteilinfektion= en
esInfección necrosante de partes blandas= en
itInfezione necrotizzante dei tessuti molli
nlNecrotiserende infectie van weke delen= en
ptInfecção necrotizante dos tecidos moles= en
plMartwicze zakażenie tkanek miękkich= en
csNekrotizující infekce měkkých tkání= en
ukНекротична інфекція мяких тканин= en
zh坏死性软组织感染= en
trNekrotizan yumuşak doku enfeksiyonu= en

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10M72.6NTBTattributedvalidated
ICD-111B71BTNTspecificvalidated
MONDO0018602Evalidated
UMLSC2732890Evalidated
MedDRA10076637Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

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Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

Children (3):

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

0 records

No prevalence record in this release.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

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Sources for this card