Rift valley fever
- Type
- Disease
- Group
- Disorder
- Age of onset
- All ages
- Status
- active
Rift Valley fever (RVF), caused by the Rift Valley fever virus (RVFV), is an arbovirus characterized by a usually self-limiting febrile illness but that in some cases can also manifest with thrombosis, vision loss, hemorrhages and/or neurological symptoms.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Rift valley fever | |
| fr | Fièvre de la vallée du Rift | |
| de | Rift-Valley-Fieber | |
| es | Fiebre del valle del Rift | |
| it | Febbre della Rift Valley | |
| nl | Rift Valley-koorts | |
| pt | Febre do vale Rift | |
| pl | Gorączka doliny Rift | |
| cs | Horečka údolí Rift | |
| uk | Лихоманка Рифтової долини | |
| zh | 裂谷热 | |
| tr | Rift vadisi ateşi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A92.4 | E | specific | validated |
| ICD-11 | 1D44 | E | specific | validated |
| MONDO | 0017880 | E | validated | |
| MeSH | D012295 | E | validated | |
| UMLS | C0035613 | E | validated | |
| MedDRA | 10039143 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:341Viral hemorrhagic fever
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | — | Europe | Class only | Validated | European Centre for Disease prevention and Control 2011[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
44 annotations · validated 2021-09-10| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001945 | Fever | |
| HP:0003237 | Increased circulating IgG level | |
| HP:0020071 | Viremia | |
| Frequent (79-30%) | ||
| HP:0002039 | Anorexia | |
| Occasional (29-5%) | ||
| HP:0000478 | Abnormality of the eye | |
| HP:0003496 | Increased circulating IgM level | |
| HP:0001324 | Muscle weakness | |
| HP:0200026 | Ocular pain | |
| HP:0032323 | Periodic fever | |
| HP:0000613 | Photophobia | |
| HP:0007663 | Reduced visual acuity | |
| HP:0000573 | Retinal hemorrhage | |
| HP:0025188 | Retinal vasculitis | |
| HP:0032118 | Retinitis | |
| HP:0000575 | Scotoma | |
| Very rare (<4-1%) | ||
| HP:0001892 | Abnormal bleeding | |
| HP:0001977 | Abnormal thrombosis | |
| HP:0001903 | Anemia | |
| HP:0003418 | Back pain | |
| HP:0012229 | CSF pleocytosis | |
| HP:0025013 | Decerebrate rigidity | |
| HP:0002910 | Elevated circulating hepatic transaminase concentration | |
| HP:0003781 | Excessive salivation | |
| HP:0000225 | Gingival bleeding | |
| HP:0000738 | Hallucinations | |
| HP:0002315 | Headache | |
| HP:0002248 | Hematemesis | |
| HP:0000790 | Hematuria | |
| HP:0001269 | Hemiparesis | |
| HP:0012115 | Hepatitis | |
| HP:0002383 | Infectious encephalitis | |
| HP:0000952 | Jaundice | |
| HP:0040049 | Macular edema | |
| HP:0002249 | Melena | |
| HP:0003470 | Paralysis | |
| HP:0002385 | Paraparesis | |
| HP:0005542 | Prolonged whole-blood clotting time | |
| HP:0004372 | Reduced consciousness | |
| HP:0031691 | Severe viral infection | |
| HP:0000988 | Skin rash | |
| HP:0005268 | Spontaneous abortion | |
| HP:0001873 | Thrombocytopenia | |
| HP:0000554 | Uveitis | |
| HP:0002321 | Vertigo | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 32816810[PMID]_31310198[PMID]_28457351[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/319251
- This record as JSON: /data/d/319251.json