Secondary hypereosinophilic syndrome
Synonyms: HES-R · Reactive hypereosinophilic syndrome · Secondary HES
- Type
- Disease
- Group
- Disorder
- Age of onset
- All ages
- Status
- active
A rare hypereosinophilic syndrome characterized by hypereosinophilia produced by reactive/non-clonal eosinophils secondary to an underlying medical condition and persisting for at least six months. The disorder can derive from non-neoplastic conditions (such as chronic infections and infestations, allergic reactions, intoxications, or autoimmune and chronic inflammatory disorders) or from neoplasms including non-myeloid malignancies, among others. It is associated with signs of organ infiltration, dysfunction, and damage. Clinical manifestations are highly variable, depending on the organ systems involved, and most commonly include dermatologic, pulmonary, cardiac, gastrointestinal, and cerebral manifestations.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Secondary hypereosinophilic syndrome | HES-R · Reactive hypereosinophilic syndrome · Secondary HES |
| fr | Syndrome hyperéosinophilique secondaire | SHE-R · Syndrome hyperéosinophilique réactif |
| de | Hypereosinophiles Syndrom, sekundäres | HES, sekundäres · HESR · Hypereosinophiles Syndrom, reaktives |
| es | Síndrome hipereosinofílico secundario | HES secundario · HESR · Síndrome hipereosinofílico reactivo |
| it | Sindrome ipereosinofila secondaria | HES secondaria · HESR · Sindrome ipereosinofila reattiva |
| nl | Secundair hypereosinofiel syndroom | HESR · Reactief hypereosinofiel syndroom · Secundaire HES |
| pt | Síndrome hipereosinofílica secundária | HES secundária · HES-R · Síndrome hipereosinofílica reativa |
| pl | Wtórny zespół hipereozynofilowy | HES-R · Reaktywny zespół hipereozynofilowy · Wtórny HES |
| cs | Sekundární hypereozinofilní syndrom | HES-R · Reaktivní hypereozinofilní syndrom · Sekundární HES |
| uk | Вторинний гіпереозинофільний синдром | HES-R · Реактивний гіпереозинофільний синдром · Вторинна HES |
| zh | 继发性嗜酸性粒细胞增多综合征 | 反应性嗜酸性粒细胞增多综合征 |
| tr | Sekonder hipereozinofilik sendrom | HES-R · Sekonder HES · Reaktif hipereozinofilik sendrom |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D47.5 | NTBT | attributed | validated |
| MONDO | 0017834 | E | validated | |
| UMLS | C5679897 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:168956Hypereosinophilic syndrome
rare cardiac diseases; rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders
Children (1):
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/314962
- This record as JSON: /data/d/314962.json