ORPHA:168956
Hypereosinophilic syndrome
Synonyms: HES
- Type
- Clinical group
- Group
- Group of disorders
- Inheritance
- Not applicable, Unknown
- Age of onset
- All ages
- Status
- active
Hypereosinophilic syndrome (HES) constitutes a rare and heterogeneous group of disorders, defined as persistent and marked blood eosinophilia and/or tissue eosinophilia associated with a wide range of clinical manifestations reflecting eosinophil-induced tissue/organ damage.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Hypereosinophilic syndrome | HES |
| fr | Syndrome hyperéosinophilique | = en |
| de | Hypereosinophile Syndrome | |
| es | Síndromes hipereosinofílicos | |
| it | Sindrome da ipereosinofilia | |
| nl | Hypereosinofiel syndroom | |
| pt | Síndromes hipereosinofílicos | |
| pl | Zespół hipereozynofilowy | = en |
| cs | Hypereozinofilní syndrom | = en |
| uk | Гіпереозинофільний синдром | ГЕС |
| zh | 嗜酸性粒细胞增多综合征 | = en |
| tr | Hipereozinofilik sendrom | = en |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| MONDO | 0015691 | E | validated | |
| MONDO | 15691 | E | validated | |
| MeSH | D017681 | E | validated | |
| UMLS | C1540912 | E | validated | |
| GARD | 2804 | E | validated | |
| MedDRA | 10048643 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:98274Myeloproliferative neoplasm
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders - ORPHA:217720Non-familial restrictive cardiomyopathy
rare cardiac diseases
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
4 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | 0.027 / 100 000 | United States | Value and class | Validated | 20639012[PMID] |
| Point prevalence | Unknown | — | Europe | Class only | Validated | ORPHANET |
| Point prevalence | 1-9 / 100 000 | 3.3 / 100 000 | United States | Value and class | Validated | 20639012[PMID]_[EXPERT] |
| Annual incidence | <1 / 1 000 000 | — | Europe | Class only | Validated | RARECARE surveillance of rare cancers in Europe[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/168956
- This record as JSON: /data/d/168956.json