ORPHA:254504
Inhalational botulism
Synonyms: Inhalation botulism
- Type
- Clinical subtype
- Group
- Subtype of disorder
- Age of onset
- Adult
- Status
- active
Inhalational botulism is a man-made form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis caused by botulinum neurotoxins (BoNTs).
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Inhalational botulism | Inhalation botulism |
| fr | Botulisme par inhalation | |
| de | Botulismus, inhalativer | |
| es | Botulismo por inhalación | |
| it | Botulismo da inalazione | |
| nl | Inhalatiebotulisme | |
| pt | Botulismo inalatório | Botulismo por inalação |
| pl | Botulizm inhalacyjny | = en |
| cs | Inhalační botulismus | = en |
| uk | Інгаляційний ботулізм | Інгаляційний ботулізм |
| zh | 吸入性肉毒中毒 | 吸入性肉毒中毒 |
| tr | İnhalasyon botulizmi | İnhalasyon botulizmi |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A05.1 | NTBT | attributed | validated |
| ICD-11 | 1A11.1 | NTBT | index | validated |
| MONDO | 0016777 | E | validated | |
| UMLS | C1443900 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:1267Botulism
rare neurological diseases; rare ophthalmic disorders; rare infectious diseases
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 10 cases | Worldwide | Case(s) | Validated | [EXPERT] | |
| Point prevalence | <1 / 1 000 000 | — | Worldwide | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
13 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0002019 | Constipation | |
| HP:0006824 | Cranial nerve paralysis | |
| HP:0000651 | Diplopia | |
| HP:0012378 | Fatigue | |
| HP:0001324 | Muscle weakness | |
| HP:0011499 | Mydriasis | |
| HP:0003470 | Paralysis | |
| HP:0000508 | Ptosis | |
| HP:0000016 | Urinary retention | |
| HP:0000217 | Xerostomia | |
| Frequent (79-30%) | ||
| HP:0002014 | Diarrhea | |
| HP:0002094 | Dyspnea | |
| HP:0002017 | Nausea and vomiting | |
Run the differential on the 10 obligate / very frequent terms
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/254504
- This record as JSON: /data/d/254504.json