Thoracic outlet syndrome
Synonyms: TOS · Thoracic outlet compression syndrome
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adult, Elderly
- Status
- active
Thoracic outlet syndrome (TOS) is a group of disorders characterized by paresthesias, pain and weakness of the upper extremities due to compression, tension or inflammation of the neurovascular bundle as it passes through the thoracic outlet. There are 3 forms of TOS with different clinical pictures and etiologies: neurogenic TOS (NTOS) that can be divided into true or disputed forms, arterial TOS (ATOS) and venous TOS (VTOS).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Thoracic outlet syndrome | TOS · Thoracic outlet compression syndrome |
| fr | Syndrome du défilé thoracique | SDT · Syndrome de la traversée cervico-thoraco-brachiale · Syndrome du défilé cervico-thoraco-brachial · TOS |
| de | Thoracic-outlet-Syndrom | |
| es | Síndrome de la salida torácica | SST · TOS |
| it | Sindrome dello stretto toracico | TOS |
| nl | Thoracic outlet-syndroom | Thoracic outlet-compressiesyndroom · TOS |
| pt | Síndrome do canal torácico | |
| pl | Zespół górnego otworu klatki piersiowej | TOS · Zespół uciskowy górnego otworu klatki |
| cs | Syndrom horní hrudní apertury | TOS · Kompresivní syndrom horní hrudní apertury |
| uk | Синдром грудного виходу | Синдром здавлення грудного отвору легеневої артерії · TOS |
| zh | 胸廓出口综合征 | 胸廓出口压迫综合征 |
| tr | Torasik çıkış sendromu | TOS · Torasik çıkış kompresyon sendromu |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G54.0 | NTBT | inclusion | validated |
| ICD-11 | 8B91.Y | NTBT | index | validated |
| MONDO | 0005979 | E | validated | |
| MeSH | D013901 | E | validated | |
| UMLS | C0039984 | E | validated | |
| GARD | 7759 | E | validated | |
| MedDRA | 10048627 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:97962Rare surgical thoracic disease
rare surgical thoracic diseases
Codes that Orphanet moved or referred to this one:
- ORPHA:100072OBSOLETE: True vascular thoracic outlet syndrome referred to · inactive
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
11 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0003401 | Paresthesia | |
| Frequent (79-30%) | ||
| HP:0000772 | Abnormal rib morphology | |
| HP:0002829 | Arthralgia | |
| HP:0000969 | Edema | |
| HP:0001324 | Muscle weakness | |
| HP:0003326 | Myalgia | |
| Occasional (29-5%) | ||
| HP:0003457 | EMG abnormality | |
| HP:0003394 | Muscle spasm | |
| HP:0000763 | Sensory neuropathy | |
| HP:0002619 | Varicose veins | |
| HP:0004936 | Venous thrombosis | |
Run the differential on the 1 obligate / very frequent terms
Annotation source: 26251937[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/97330
- This record as JSON: /data/d/97330.json