raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:97292

Cardiogenic shock

Type
Particular clinical situation in a disease or syndrome
Group
Disorder
Inheritance
Not applicable
Age of onset
Adolescent, Adult, Childhood, Elderly
Status
active

A rare, cardiac condition characterized by severely decreased cardiac output, hypoperfusion and end-organ dysfunction, in the presence of adequate intravascular volume. The clinical presentation is variable and may range from subtle hemodynamic alterations to overt cardiovascular collapse. Commonly reported features include dyspnea, crackles, elevated jugular venous pressure, altered mental state, abnormal pulse pressure, oliguria, cold extremities, and increased serum lactate levels.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enCardiogenic shock
frChoc cardiogénique
deKardiogener Schock
esShock cardiogénicoChoque cardiogénico
itShock cardiogeno
nlCardiogene shock
ptTratamento de choque cardiogénico
plWstrząs kardiogenny
csKardiogenní šok
ukКардіогенний шок
zh心源性休克
trKardiyojenik şok

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10R57.0Especificvalidated
ICD-11MG40.0Especificvalidated
MONDO0800175Evalidated
MeSHD012770Evalidated
UMLSC0036980Evalidated
MedDRA10007625Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

1 record
TypeClassValueAreaQualificationValidationSource
Point prevalence1-5 / 10 00040 / 100 000EuropeValue and classValidatedEuropean Medicines Agency 2008[OTHER]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

30 annotations · validated 2023-08-10
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0003115Abnormal EKG
HP:0005162Abnormal left ventricular function
HP:0002615Hypotension
HP:0009805Low-output congestive heart failure
Frequent (79-30%)
HP:0011675Arrhythmia
HP:0001695Cardiac arrest
HP:0001635Congestive heart failure
HP:0030830Crackles
HP:0000961Cyanosis
HP:0002094Dyspnea
HP:0000969Edema
HP:0030848Elevated jugular venous pressure
HP:0012418Hypoxemia
HP:0006670Impaired myocardial contractility
HP:0030876Increased pulmonary capillary wedge pressure
HP:0030851Low pulse pressure
HP:0001658Myocardial infarction
HP:0100520Oliguria
HP:0012764Orthopnea
HP:0004372Reduced consciousness
Occasional (29-5%)
HP:0001289Confusion
HP:0003259Elevated circulating creatinine concentration
HP:0002240Hepatomegaly
HP:0002151Increased circulating lactate concentration
HP:0001942Metabolic acidosis
HP:0001653Mitral regurgitation
HP:0012251ST segment elevation
HP:0002321Vertigo
Very rare (<4-1%)
HP:0001259Coma
HP:0001708Right ventricular failure

Run the differential on the 4 obligate / very frequent terms

Annotation source: 29412021[PMID]_28923988[PMID_29173681[PMID]_30947630[PMID]

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Sources for this card