Adenohypophysitis
Synonyms: Anterior pituitary hypophysitis
- Type
- Disease
- Group
- Disorder
- Age of onset
- Adolescent, Adult
- Status
- active
A rare, acquired pituitary hormone deficiency, a type of primary hypophysitis characterized by an inflammation of anterior pituitary. Clinical presentation is variable and includes headaches, visual disturbances, symptoms of adrenal insufficiency, hyperprolactinemia, hypothyroidism and hypogonadism. It most commonly affects young women during pregnancy or postpartum period.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Adenohypophysitis | Anterior pituitary hypophysitis |
| fr | Adénohypophysite | Hypophysite de l'hypophyse antérieure |
| de | Adenohypophysitis, lymphozytische | |
| es | Adenohipofisitis | Hipofisitis pituitaria anterior |
| it | Adenoipofisite | Ipofisite dell'ipofisi anteriore |
| nl | Adenohypofysitis | Anterieure pituïtaire hypofysitis |
| pt | Adeno-hipofisite linfocítica | |
| pl | Zapalenie gruczołowej części przysadki | Zapalenie przedniej części przysadki |
| cs | Adenohypofyzitida | Zánět předního laloku hypofýzy |
| uk | Аденогіпофізит | Гіпофіз передньої частки гіпофіза |
| zh | 腺垂体炎 | 垂体前叶炎 |
| tr | Adenohipofizit | Anterior hipofiz hipofiziti |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | E23.6 | NTBT | attributed | validated |
| ICD-11 | 5A61.0 | NTBT | attributed | validated |
| MONDO | 0019838 | E | validated | |
| UMLS | C5190880 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:95506Primary hypophysitis
rare endocrine diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
0 recordsNo prevalence record in this release.
HPO phenotypes
32 annotations · validated 2017-06-30| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0000871 | Panhypopituitarism | |
| Frequent (79-30%) | ||
| HP:0012504 | Abnormal size of pituitary gland | |
| HP:0012696 | Abnormal thalamic MRI signal intensity | |
| HP:0011748 | Adrenocorticotropic hormone deficiency | |
| HP:0011735 | Adrenocorticotropin deficient adrenal insufficiency | |
| HP:0000141 | Amenorrhea | |
| HP:0000622 | Blurred vision | |
| HP:0008163 | Decreased circulating cortisol level | |
| HP:0030018 | Decreased female libido | |
| HP:0040306 | Decreased male libido | |
| HP:0008214 | Decreased serum estradiol | |
| HP:0040171 | Decreased serum testosterone concentration | |
| HP:0008213 | Gonadotropin deficiency | |
| HP:0002315 | Headache | |
| HP:0003158 | Hyposthenuria | |
| HP:0000802 | Impotence | |
| HP:0000870 | Increased circulating prolactin concentration | |
| HP:0002018 | Nausea | |
| HP:0001895 | Normochromic anemia | |
| HP:0001278 | Orthostatic hypotension | |
| HP:0000980 | Pallor | |
| HP:0008245 | Pituitary hypothyroidism | |
| HP:0007987 | Progressive visual field defects | |
| HP:0008240 | Secondary growth hormone deficiency | |
| Occasional (29-5%) | ||
| HP:0003493 | Antinuclear antibody positivity | |
| HP:0007041 | Chronic lymphocytic meningitis | |
| HP:0000651 | Diplopia | |
| HP:0000872 | Hashimoto thyroiditis | |
| HP:0002902 | Hyponatremia | |
| HP:0004396 | Poor appetite | |
| HP:0008202 | Reduced circulating prolactin concentration | |
| HP:0000407 | Sensorineural hearing impairment | |
Run the differential on the 1 obligate / very frequent terms
Annotation source: 23885185[PMID]_27008424[PMID]_18987830[PMID]_17273922[PMID]_14606714[PMID]_27165294[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/95512
- This record as JSON: /data/d/95512.json