Premature closure of the arterial duct
Synonyms: Premature closure of the patent ductus arteriosus
- Type
- Morphological anomaly
- Group
- Disorder
- Status
- active
Premature closure of the arterial duct is a rare arterial duct anomaly, defined as a significant constriction or closure of the fetal arterial duct in the absence of structural heart defects with pathognomonic features of increased right ventricular afterload, tricuspid regurgitation and, consequently, right atrial dilation and right ventricular hypertrophy. The severity of symptoms is related to the degree and rate of ductal constriction and ranges from mild postnatal respiratory distress to development of ventricular failure with fetal hydrops and intrauterine death or severe cardiopulmonary compromise in the postnatal period. It may be associated with a prenatal exposure to cyclooxygenase inhibitors or corticosteroids.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Premature closure of the arterial duct | Premature closure of the patent ductus arteriosus |
| fr | Fermeture anténatale du canal artériel | |
| de | Ductus arteriosus, vorzeitiger Verschluss des | |
| es | Cierre prematuro del ductus arterioso | Cierre prematuro del conducto arterioso persistente · Constricción prematura del ductus arterioso |
| it | Chiusura prematura del dotto arterioso | Chiusura prematura del dotto arterioso |
| nl | Premature sluiting van ductus arteriosus | Vroegtijdige sluiting van persisterende ductus arteriosus |
| pt | Encerramento prematuro do canal arterial | |
| pl | Przedwczesne zamknięcie przewodu tętniczego | Przedwczesne zamknięcie przetrwałego przewodu tętniczego |
| cs | Předčasný uzávěr Botallovy dučeje | Předčasný uzávěr patens ductus arteriosus · Předčasný uzávěr ductus arteriosus |
| uk | Передчасне закриття артеріальної протоки | Передчасне закриття відкритої артеріальної протоки |
| zh | 动脉导管过早闭合 | 动脉导管过早闭合 |
| tr | Arteriyel kanalın erken kapanması | Patent duktus arteriyozusun erken kapanması |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | Q25.8 | NTBT | attributed | validated |
| ICD-11 | LA8B.Y | NTBT | index | validated |
| MONDO | 0019823 | E | validated | |
| UMLS | C3532264 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:95485Arterial duct anomaly
rare developmental anomalies during embryogenesis; rare cardiac malformations; rare circulatory system diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
0 recordsNo prevalence record in this release.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/95486
- This record as JSON: /data/d/95486.json