Neovascular glaucoma
- Type
- Particular clinical situation in a disease or syndrome
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult, Elderly
- Status
- active
Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uveitis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Neovascular glaucoma | |
| fr | Glaucome néovasculaire | |
| de | Glaukom, neovaskuläres | |
| es | Glaucoma neovascular | |
| it | Glaucoma neovascolare | |
| nl | Neovasculair glaucoom | |
| pt | Glaucoma neovascular | |
| pl | Jaskra neowaskularna | |
| cs | Neovaskulární glaukom | |
| uk | Неоваскулярна глаукома | |
| zh | 新生血管性青光眼 | |
| tr | Neovasküler glokom |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | H40.5 | NTBT | attributed | validated |
| ICD-11 | 9C61.32 | E | specific | validated |
| MONDO | 0019783 | E | validated | |
| MeSH | D015355 | E | validated | |
| UMLS | C0017609 | E | validated | |
| MedDRA | 10062891 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:98631Congenital malformation of the eye with glaucoma as a major feature
rare developmental anomalies during embryogenesis; rare ophthalmic disorders
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 24.4 / 100 000 | Europe | Value and class | Validated | European Medicines Agency 2003[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
20 annotations · validated 2023-09-11| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Obligate (100%) | ||
| HP:0000501 | Glaucoma | |
| Very frequent (99-80%) | ||
| HP:0011497 | Iris neovascularization | |
| HP:0012636 | Retinal vein occlusion | |
| HP:0000572 | Visual loss | |
| Frequent (79-30%) | ||
| HP:0000587 | Abnormal optic nerve morphology | |
| HP:0000553 | Abnormal uvea morphology | |
| HP:3000032 | Abnormality of central retinal artery | |
| HP:0020166 | Central retinal vein occlusion | |
| HP:0007906 | Ocular hypertension | |
| HP:0200026 | Ocular pain | |
| HP:0000613 | Photophobia | |
| HP:0000488 | Retinopathy | |
| HP:0030532 | Visual acuity test abnormality | |
| Occasional (29-5%) | ||
| HP:0000593 | Abnormal anterior chamber morphology | |
| HP:0004329 | Abnormality of the posterior segment of the globe | |
| HP:0030953 | Conjunctival hyperemia | |
| HP:0012040 | Corneal stromal edema | |
| HP:0007850 | Retinal vascular proliferation | |
| HP:0025358 | Uveal ectropion | |
| Very rare (<4-1%) | ||
| HP:0000541 | Retinal detachment | |
Run the differential on the 4 obligate / very frequent terms
Annotation source: 33595466[PMID]_26501989[PMID]_1697175[PMID]_27895936[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/94058
- This record as JSON: /data/d/94058.json