{"orpha":94058,"name":"Neovascular glaucoma","type":"Particular clinical situation in a disease or syndrome","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uveitis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-94058/","orphanet_url":"https://www.orpha.net/en/disease/detail/94058","names":{"fr":{"name":"Glaucome néovasculaire","definition":"Type le plus courant de glaucome secondaire, généralement causé par une rétinopathie diabétique, une occlusion de la veine centrale de la rétine et une obstruction de l'artère carotide, mais dans certains cas causé par un traumatisme, une uvéite ou des tumeurs oculaires. Il se caractérise par une douleur oculaire intense, un glaucome à angle fermé avec synéchies, une pression intraoculaire élevée, à l'origine d'une perte de vision."},"de":{"name":"Glaukom, neovaskuläres","definition":"Das Neovaskuläre Glaukom ist der häufigste Typ des sekundären Glaukoms, in der Regel verursacht durch diabetische Retinopathie, Verschluss der zentralen Netzhautvene oder der Carotisarterie, manchmal aber auch durch Trauma, Uveitis oder Augentumoren. Merkmale sind schwere Schmerzen in den Augen, Glaukom mit Kammerwinkel-Synechien, hoher Augeninnendruck und Visusverlust."},"es":{"name":"Glaucoma neovascular","definition":"El glaucoma neovascular es el tipo más frecuente de glaucoma secundario, normalmente causado por una retinopatía diabética, oclusión de la vena central de la retina y obstrucción de la arteria carótida pero a veces por trauma, uveítis o tumores oculares, y se caracteriza por dolor de ojo intenso, glaucoma de ángulo cerrado por sinequia, presión intraocular alta y da lugar a pérdida de visión."},"it":{"name":"Glaucoma neovascolare","definition":"Il glaucoma neovascolare è la forma più comune del glaucoma secondario, di solito causata da retinopatia diabetica, occlusione della vena centrale della retina e ostruzione dell'arteria carotide e, a volte, da traumi, uveite o tumori oculari. È caratterizzata da grave dolore oculare, glaucoma ad angolo chiuso per sinechia e pressione intraoculare elevata. Esita nella perdita della vista."},"nl":{"name":"Neovasculair glaucoom","definition":"Het meest gangbare type van secundair glaucoom, meestal veroorzaakt door diabetische retinopathie, occlusie van centrale retinale vene en obstructie van arteria carotis, maar soms door trauma, uveïtis of tumoren van oog, en gekenmerkt door ernstige pijn van oog, geslotenkamerhoekglaucoom door synechie, hoge intraoculaire druk, en verlies van gezichtsvermogen."},"pt":{"name":"Glaucoma neovascular"},"pl":{"name":"Jaskra neowaskularna"},"cs":{"name":"Neovaskulární glaukom"},"uk":{"name":"Неоваскулярна глаукома","definition":"Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uvietis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision."},"zh":{"name":"新生血管性青光眼","definition":"新生血管性青光眼是最常见的继发性青光眼，通常由糖尿病视网膜病变、视网膜中央静脉阻塞和颈动脉阻塞引起，但有时也可由外伤、葡萄膜炎或眼部肿瘤引起，其特点是重度眼痛、房角粘连所致闭角型青光眼、高眼压并导致视力丧失。"},"tr":{"name":"Neovasküler glokom"}},"xrefs":[{"source":"ICD-10","code":"H40.5","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9C61.32","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"700864997"},{"source":"MONDO","code":"0019783","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D015355","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0017609","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10062891","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":98631,"name":"Congenital malformation of the eye with glaucoma as a major feature","classifications":[147,189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult","Elderly"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":24.4,"area":"Europe","status":"Validated","source":"European Medicines Agency 2003[OTHER]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2023-09-11","source":"33595466[PMID]_26501989[PMID]_1697175[PMID]_27895936[PMID]","terms":[{"hpo":"HP:0000501","label":"Glaucoma","frequency":"Obligate (100%)","criteria":null},{"hpo":"HP:0011497","label":"Iris neovascularization","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0012636","label":"Retinal vein occlusion","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000572","label":"Visual loss","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000587","label":"Abnormal optic nerve morphology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000553","label":"Abnormal uvea morphology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:3000032","label":"Abnormality of central retinal artery","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0020166","label":"Central retinal vein occlusion","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0007906","label":"Ocular hypertension","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0200026","label":"Ocular pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000613","label":"Photophobia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000488","label":"Retinopathy","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0030532","label":"Visual acuity test abnormality","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000593","label":"Abnormal anterior chamber morphology","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0004329","label":"Abnormality of the posterior segment of the globe","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030953","label":"Conjunctival hyperemia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012040","label":"Corneal stromal edema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007850","label":"Retinal vascular proliferation","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025358","label":"Uveal ectropion","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000541","label":"Retinal detachment","frequency":"Very rare (<4-1%)","criteria":null}]}}