Relapsing fever
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
An infectious disease, rare in Europe, characterized by relapsing fever accompanied by headaches, vomiting and myalgia lasting 2-7 days, with afebrile intervals of up to 10 days. It is caused by bacterial species of the genus <i>Borrelia</i>, and transmitted by ticks (tick-borne relapsing fever; TBRF) and lice (louse-borne relapsing fever; LBRF).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Relapsing fever | |
| fr | Fièvre récurrente infectieuse | |
| de | Rückfallfieber | |
| es | Fiebre recurrente | |
| it | Febbre ricorrente | |
| nl | Terugkerende koorts | Febris recurrens |
| pt | Febre recorrente | |
| pl | Dur powrotny | |
| cs | Návratná horečka | |
| uk | Рецидивуюча лихоманка | |
| zh | 回归热 | |
| tr | Tekrarlayan ateş |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A68.0 | BTNT | specific | validated |
| ICD-10 | A68.1 | BTNT | specific | validated |
| ICD-10 | A68.9 | BTNT | specific | validated |
| ICD-11 | 1C1J | E | specific | validated |
| MONDO | 0019633 | E | validated | |
| MeSH | D012061 | E | validated | |
| UMLS | C0035021 | E | validated | |
| MedDRA | 10038300 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163582Rare bacterial infectious disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
32 annotations · validated 2019-10-25| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| HP:0001945 | Fever | |
| HP:0003573 | Increased total bilirubin | |
| HP:0001873 | Thrombocytopenia | |
| Frequent (79-30%) | ||
| HP:0001903 | Anemia | |
| HP:0002910 | Elevated circulating hepatic transaminase concentration | |
| HP:0002315 | Headache | |
| HP:0025435 | Increased circulating lactate dehydrogenase concentration | |
| HP:0001974 | Increased total leukocyte count | |
| HP:0000952 | Jaundice | |
| HP:0003326 | Myalgia | |
| Occasional (29-5%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0001892 | Abnormal bleeding | |
| HP:0000079 | Abnormality of the urinary system | |
| HP:0001919 | Acute kidney injury | |
| HP:0002829 | Arthralgia | |
| HP:0025143 | Chills | |
| HP:0012735 | Cough | |
| HP:0003259 | Elevated circulating creatinine concentration | |
| HP:0012378 | Fatigue | |
| HP:0002615 | Hypotension | |
| HP:0001882 | Leukopenia | |
| HP:0031179 | Nuchal rigidity | |
| HP:0001649 | Tachycardia | |
| HP:0002013 | Vomiting | |
| Very rare (<4-1%) | ||
| HP:0002014 | Diarrhea | |
| HP:0000421 | Epistaxis | |
| HP:0000790 | Hematuria | |
| HP:0002105 | Hemoptysis | |
| HP:0011899 | Hyperfibrinogenemia | |
| HP:0011897 | Neutrophilia | |
| HP:0008151 | Prolonged prothrombin time | |
Run the differential on the 4 obligate / very frequent terms
Annotation source: 31187963[PMID]_29016302[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/91547
- This record as JSON: /data/d/91547.json