Hepatitis B reinfection following liver transplantation
- Type
- Particular clinical situation in a disease or syndrome
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare hepatic disease characterized by graft infection with the hepatitis B virus (HBV) after liver transplantation, due to persistence and reactivation of HBV in extrahepatic sites (also despite previous clearance of the HBs antigen from serum, as shown by laboratory examination), followed by re-invasion of the graft. It may develop between two weeks and several years post transplantation. Clinico-pathological features are variable and range from mild self-limited hepatitis, chronic active hepatitis, and fulminant hepatitis, to fibrosing cholestatic hepatitis. The condition is associated with significantly reduced graft survival rates and overall patient survival.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Hepatitis B reinfection following liver transplantation | |
| fr | Réinfection par l'hépatite B après transplantation hépatique | |
| de | Hepatitis-B-Reinfektion nach Lebertransplantation | |
| es | Reinfección por hepatitis B después de trasplante hepático | |
| it | Nuova infezione da epatite B dopo trapianto del fegato | |
| nl | Hepatitis B-herinfectie na levertransplantatie | |
| pt | Re-infeção de hepatite B após transplante hepático | |
| pl | Powtórne zakażenie wirusem zapalenia wątroby typu B po transplantacji wątroby | |
| cs | Reinfekce virem hepatitidy B následující po transplantaci jater | |
| uk | Реінфекція гепатитом В після трансплантації печінки | |
| zh | 肝移植术后乙型肝炎病毒再感染 | |
| tr | Karaciğer nakli sonrası Hepatit B reenfeksiyonu |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | B18.0 | NTBT | attributed | not yet validated |
| ICD-11 | 1E51.0Y | NTBT | attributed | validated |
| UMLS | C5681345 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:565779Rare disorder potentially indicated for transplant or complication after transplantation
rare transplant-related disorders - ORPHA:57146Rare hepatic disease
rare hepatic diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 2 / 100 000 | Europe | Value and class | Validated | European Medicines Agency 2004[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/90073
- This record as JSON: /data/d/90073.json