ORPHA:90036
Mixed-type autoimmune hemolytic anemia
Synonyms: Mixed AIHA
- Type
- Disease
- Group
- Disorder
- Inheritance
- Multigenic/multifactorial
- Age of onset
- All ages
- Status
- active
Mixed autoimmune hemolytic anemia is a type of autoimmune hemolytic anemia (AIHA) defined by the presence of both warm and cold autoantibodies, which have a deleterious effect on red blood cells at either body temperature or at lower temperatures.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Mixed-type autoimmune hemolytic anemia | Mixed AIHA |
| fr | Anémie hémolytique auto-immune mixte | AIHA mixte |
| de | Anämie, autoimmun-hämolytische, gemischter Typ | |
| es | Anemia hemolítica autoinmune tipo mixto | AHAI tipo mixto · AIHA tipo mixto |
| it | Anemia emolitica autoimmune, tipo misto | AIHA mista |
| nl | Auto-immune hemolytische anemie, gemengd type | Gemengde AIHA |
| pt | Anemia hemolítica autoimune, tipo misto | |
| pl | Niedokrwistość autoimmunohemolityczna typu mieszanego | AIHA mieszana |
| cs | Autoimunitní hemolytická anémie smíšeného typu | Smíšená AIHA |
| uk | Аутоімунна гемолітична анемія змішаного типу | Змішаний АМСЗ |
| zh | 混合型自身免疫性溶血性贫血 | 混合型AIHA |
| tr | Karma tipte otoimmün hemolitik anemi | Karma AIHA |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D59.1 | NTBT | attributed | validated |
| ICD-11 | 3A20.2 | E | specific | validated |
| MONDO | 0019534 | E | validated | |
| UMLS | C4305257 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:98375Autoimmune hemolytic anemia
rare hematological diseases
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | <1 / 1 000 000 | — | Europe | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
14 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001890 | Autoimmune hemolytic anemia | |
| HP:0002960 | Autoimmunity | |
| HP:0002875 | Exertional dyspnea | |
| HP:0012378 | Fatigue | |
| HP:0001324 | Muscle weakness | |
| HP:0000980 | Pallor | |
| Frequent (79-30%) | ||
| HP:0002829 | Arthralgia | |
| HP:0002665 | Lymphoma | |
| HP:0000988 | Skin rash | |
| HP:0002725 | Systemic lupus erythematosus | |
| Occasional (29-5%) | ||
| HP:0012086 | Abnormal urinary color | |
| HP:0001945 | Fever | |
| HP:0003573 | Increased total bilirubin | |
| HP:0001649 | Tachycardia | |
Run the differential on the 6 obligate / very frequent terms
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/90036
- This record as JSON: /data/d/90036.json