Autoimmune hemolytic anemia, warm type
Synonyms: Warm AIHA · wAHA · wAIHA
- Type
- Disease
- Group
- Disorder
- Inheritance
- Multigenic/multifactorial
- Age of onset
- All ages
- Status
- active
Warm autoimmune hemolytic anemia is the most common form of autoimmune hemolytic anemia defined by the presence of warm autoantibodies against red blood cells (autoantibodies that are active at temperatures between 37-40°C).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Autoimmune hemolytic anemia, warm type | Warm AIHA · wAHA · wAIHA |
| fr | Anémie hémolytique auto-immune à auto-anticorps chauds | AIHA chaude · wAHA · wAIHA |
| de | Anämie, autoimmun-hämolytische, Wärme-Typ | |
| es | Anemia autoinmune hemolítica tipo caliente | AHAI caliente · AIHA caliente · wAHA · wAIHA |
| it | Anemia emolitica autoimmune, tipo caldo | AIHA calda · wAHA · wAIHA |
| nl | Auto-immune hemolytische anemie, warmte-type | Auto-immune hemolytische anemie met warme auto-antilichamen · Warme AIHA · wAHA · wAIHA |
| pt | Anemia hemolítica autoimune, tipo quente | |
| pl | Niedokrwistość autoimmunohemolityczna typu ciepłego | wAHA · wAIHA · Warm AIHA |
| cs | Autoimunitní hemolytická anémie s tepelnými protilátkami | Tepelná AIHA · wAHA · wAIHA |
| uk | Аутоімунна гемолітична анемія теплого типу | wAHA · wAIHA · Теплий AIHA |
| zh | 温抗体型自身免疫性溶血性贫血 | 温抗体型AIHA |
| tr | Otoimmün hemolitik anemi, ılık tip | WAHA · WAIHA · Warm AIHA |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D59.1 | NTBT | inclusion | validated |
| ICD-11 | 3A20.0 | E | specific | validated |
| MONDO | 0019532 | E | validated | |
| UMLS | C0272118 | E | validated | |
| GARD | 7876 | E | validated | |
| MedDRA | 10047822 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:98375Autoimmune hemolytic anemia
rare hematological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | — | Europe | Class only | Not yet validated | ORPHANET |
| Annual incidence | 1-9 / 100 000 | 2.4 / 100 000 | France | Value and class | Validated | 36485114[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
27 annotations · validated 2024-10-18| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001890 | Autoimmune hemolytic anemia | |
| HP:0002960 | Autoimmunity | |
| HP:0002875 | Exertional dyspnea | |
| HP:0012378 | Fatigue | |
| HP:0002315 | Headache | |
| HP:0000980 | Pallor | |
| Frequent (79-30%) | ||
| HP:0002829 | Arthralgia | |
| HP:0020062 | Decreased hemoglobin concentration | |
| HP:0003641 | Hemoglobinuria | |
| HP:0025435 | Increased circulating lactate dehydrogenase concentration | |
| HP:0005523 | Lymphoproliferative disorder | |
| HP:0004835 | Microspherocytosis | |
| HP:0001962 | Palpitations | |
| HP:0032366 | Positive direct antiglobulin test | |
| HP:0020181 | Reduced haptoglobin level | |
| HP:0001923 | Reticulocytosis | |
| HP:0001744 | Splenomegaly | |
| HP:0008282 | Unconjugated hyperbilirubinemia | |
| Occasional (29-5%) | ||
| HP:0012086 | Abnormal urinary color | |
| HP:0100749 | Chest pain | |
| HP:0005550 | Chronic lymphatic leukemia | |
| HP:0001635 | Congestive heart failure | |
| HP:0030848 | Elevated jugular venous pressure | |
| HP:0001945 | Fever | |
| HP:0000952 | Jaundice | |
| HP:0002725 | Systemic lupus erythematosus | |
| HP:0001649 | Tachycardia | |
Run the differential on the 6 obligate / very frequent terms
Annotation source: 31412178[PMID]_26043384[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/90033
- This record as JSON: /data/d/90033.json