Methotrexate-associated lymphoproliferative disorders
Synonyms: MTX-LPD · MTX-associated lymphoproliferative disorders
- Type
- Disease
- Group
- Disorder
- Status
- active
Methotrexate-associated lymphoproliferative disorders are rare immunodeficiency-associated lymphoproliferative diseases characterized by lymphoid proliferation or lymphomas (large B-cell lymphoma, T-cell lymphoma, Hodgkin lymphoma, reactive lymphadenitis and a polymorphic post-transplant lymphoproliferative disorder) that develop in patients with different autoimmune diseases treated with methotrexate. Swelling is the predominant manifestation of the disease and regression after methotrexate withdrawal is observed in a significant proportion of patients.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Methotrexate-associated lymphoproliferative disorders | MTX-LPD · MTX-associated lymphoproliferative disorders |
| fr | Troubles lymphoprolifératifs associés au méthotréxate | Troubles lymphoprolifératifs associés au MTX |
| de | Lymphoproliferative Krankheit, Methotrexat-assozierte | Lymphoproliferative Krankheit, MTX-assoziierte · MTX-LPD |
| es | Trastornos linfoproliferativos asociados al uso de metotrexato | TLP-MTX · Trastornos linfoproliferativos asociados al MTX |
| it | Malattie linfoproliferative associate al methotrexate | |
| nl | Methotrexaatgeassocieerde lymfoproliferatieve stoornissen | MTX-LPD · MTX-geassocieerde lymfoproliferatieve stoornissen |
| pt | Doenças linfoproliferativas associadas ao metotrexato | |
| pl | Zaburzenia limfoprolifracyjne zwiazane z metotreksatem | = en |
| cs | Lymfoproliferativní nemoci asociované s methotrexátem | = en |
| uk | Метотрексат-асоційовані лімфопроліферативні розлади | МТХ-асоційовані лімфопроліферативні розлади · MTX-LPD |
| zh | 甲氨蝶呤相关淋巴增殖性疾病 | MTX相关性淋巴细胞增生性疾病 |
| tr | Metotreksat-ilişkili lenfoproliferatif bozukluklar | MTX-LPD · MTX-ilişkili lenfoproliferatif bozukluklar |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D47.7 | NTBT | attributed | validated |
| ICD-11 | 2B32.Y | NTBT | index | validated |
| MONDO | 0019483 | E | validated | |
| UMLS | C1334749 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:98290Immunodeficiency-associated lymphoproliferative disease
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
0 recordsNo prevalence record in this release.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/86904
- This record as JSON: /data/d/86904.json