ORPHA:85435
Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis
Synonyms: Juvenile idiopathic rheumatoid factor-positive polyarthritis · Juvenile polyarthritis with rheumatoid factor · Rheumatoid factor-positive polyarticular JIA
- Type
- Disease
- Group
- Disorder
- Inheritance
- Unknown
- Age of onset
- Childhood
- Status
- active
A rare form of juvenile idiopathic arthritis characterized by distal and symmetrical polyarthritis (more than 5 joints) with presence of rheumatoid factor and possible evolution towards the appearance of erosions and joint destruction.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis | Juvenile idiopathic rheumatoid factor-positive polyarthritis · Juvenile polyarthritis with rheumatoid factor · Rheumatoid factor-positive polyarticular JIA |
| fr | Arthrite juvénile idiopathique polyarticulaire avec facteur rhumatoïde | AJI polyarticulaire avec facteur rhumatoïde · Arthrite juvénile polyarticulaire avec facteur rhumatoïde · Polyarthrite juvénile avec facteur rhumatoïde · Polyarthrite juvénile facteur rhumatoïde positif |
| de | Arthritis, idiopathische juvenile polyartikuläre, Rheumafaktor-positive | Juvenile Polyarthritis mit Rheumafaktor · Polyarthritis, juvenile, Rheumafaktor-positive · Rheumafaktor-positive polyartikuläre JIA |
| es | Artritis idiopática juvenil poliarticular factor reumatoide positivo | AIJ poliarticular factor reumatoide positivo · Poliartritis idiopática juvenil factor reumatoide positivo · Poliartritis juvenil con factor reumatoide |
| it | Artrite idiopatica giovanile poliarticolare con fattore reumatoide positivo | |
| nl | Reumafactor-positieve polyarticulaire juveniele idiopathische artritis | Juveniele idiopathische reumafactor-positieve polyartritis · Juveniele polyartritis met reumafactor · Reumafactor-positieve polyarticulaire JIA |
| pt | Poliartrite com fator reumatóide | |
| pl | Wielostawowe młodzieńcze idiopatyczne zapalenie stawów z dodatnim czynnikiem reumatoidalnym | Zapalenie wielostawowe z czynnikiem reumatoidalnym · JIA z dodatnim czynnikiem reumatoidalnym · Młodzieńcze zapalenie stawów z dodatnim czynnikiem reumatoidalnym |
| cs | Juvenilní revmatoidní faktor-pozitivní polyartritida | Polyartritida s revmatoidním faktorem |
| uk | Ревматоїдний фактор-позитивний поліартикулярний ювенільний ідіопатичний артрит | Ювенільний ідіопатичний ревматоїдний фактор-позитивний поліартрит · Ювенільний поліартрит з ревматоїдним фактором · Ревматоїдний фактор-позитивний поліартикулярний ЮРА |
| zh | 类风湿因子阳性的多关节型幼年特发性关节炎 | 类风湿因子阳性的多关节型幼年特发性关节炎 |
| tr | Romatoid faktör-pozitif poliartiküler jüvenil idiyopatik artrit | Romatoid faktör-pozitif poliartiküler JIA · Romatoid faktörlü jüvenil poliartrit · Jüvenil idiyopatik romatoid faktör pozitif poliartrit |
Definition in:
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Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | M08.0 | NTBT | inclusion | validated |
| ICD-11 | FA24.1 | NTBT | index | validated |
| MONDO | 0019435 | E | validated | |
| UMLS | C4048747 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:404580Polyarticular juvenile idiopathic arthritis
rare respiratory diseases; rare systemic and rheumatological diseases; rare systemic or rheumatologic diseases of childhood; rare transplant-related disorders
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 4.2 / 100 000 | Europe | Value and class | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
19 annotations · validated 2021-05-25| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0002829 | Arthralgia | |
| HP:0001369 | Arthritis | |
| HP:0005764 | Polyarticular arthritis | |
| HP:0002923 | Rheumatoid factor positive | |
| Frequent (79-30%) | ||
| HP:0011117 | Abnormal circulating interleukin concentration | |
| HP:0005930 | Abnormality of epiphysis morphology | |
| HP:0002813 | Abnormality of limb bone morphology | |
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| HP:0003565 | Elevated erythrocyte sedimentation rate | |
| HP:0006252 | Interphalangeal joint erosions | |
| HP:0001386 | Joint swelling | |
| HP:0001376 | Limitation of joint mobility | |
| HP:0005187 | Progressive joint destruction | |
| HP:0040311 | Symetrical distal arthritis | |
| HP:0100769 | Synovitis | |
| Occasional (29-5%) | ||
| HP:0100555 | Asymmetric growth | |
| HP:0000938 | Osteopenia | |
| HP:0010588 | Premature epimetaphyseal fusion | |
| HP:0004349 | Reduced bone mineral density | |
Run the differential on the 4 obligate / very frequent terms
Annotation source: 32119492[PMID]_29582130[PMID]_27785924[PMID]_29426059[PMID]
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/85435
- This record as JSON: /data/d/85435.json