Testicular seminomatous germ cell tumor
Synonyms: Seminoma of testis · Seminomatous germ cell tumor of testis · Testicular seminoma
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult
- Status
- active
Testicular seminomatous germ cell tumor is a rare testicular germ cell tumor, most commonly presenting with a painless mass in the scrotum, with a very high cure rate if caught in the early stages.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Testicular seminomatous germ cell tumor | Seminoma of testis · Seminomatous germ cell tumor of testis · Testicular seminoma |
| fr | Tumeur testiculaire germinale séminomateuse | Séminome des testicules · Séminome testiculaire · Tumeur germinale séminomateuse des testicules |
| de | Testikulärer Keimzelltumor, seminomatöser | Seminom des Hodens · Seminom, testikuläres · Seminomatöser Keimzelltumor des Hodens |
| es | Tumor testicular de células germinales seminomatoso | Seminoma de los testículos · Seminoma testicular · Tumor de células germinales seminomatoso de los testículos |
| it | Tumore testicolare seminomatoso delle cellule germinali | Seminoma del testicolo · Seminoma testicolare · Tumore seminomatoso delle cellule germinali del testicolo |
| nl | Testiculaire seminomateuze kiemceltumor | Seminomateuze kiemceltumor van de testis · Seminoom van de testis · Testiculair seminoom |
| pt | Seminoma testicular | Disgerminoma |
| pl | Nasieniak | Nasieniak jąder |
| cs | Testikulární seminomatózní nádor ze zárodečných buněk | Seminom varlete · Testikulární seminom · Seminomatózní nádor varlete ze zárodečných buněk |
| uk | Семіноматозна герміногенна пухлина яєчка | Семінома яєчка · Семіноматозна герміногенна пухлина яєчка · Семінома яєчка |
| zh | 睾丸精原细胞瘤 | 睾丸精原细胞性生殖细胞肿瘤 |
| tr | Testis seminomatöz germ hücreli tümör | Testis seminomu · Testis seminomu · Testisin seminomatöz germ hücreli tümörü |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| OMIM | 273300 | NTBT | validated | |
| ICD-10 | C62.9 | NTBT | index | validated |
| ICD-11 | 2C80.2 | NTBT | index | validated |
| MONDO | 0003669 | E | validated | |
| UMLS | C5551428 | E | validated | |
| GARD | 4792 | E | validated | |
| MedDRA | 10062124 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:363504Germ cell tumor of testis
rare urogenital diseases; rare neoplastic diseases; rare transplant-related disorders
No children.
Codes that Orphanet moved or referred to this one:
- ORPHA:99864OBSOLETE: Classic seminoma referred to · inactive
Genes
1 direct| Gene | Association | Status | HGNC | Ensembl | OMIM | Locus | Name | Source of validation |
|---|---|---|---|---|---|---|---|---|
| KIT | Disease-causing somatic mutation(s) in | Assessed | HGNC:6342 | ENSG00000157404 | 164920 | 4q12 | KIT proto-oncogene, receptor tyrosine kinase | 14695343[PMID] |
Prevalence and incidence
3 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | 1-9 / 100 000 | 1.71 / 100 000 | Europe | Value and class | Validated | 22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER] |
| Lifetime Prevalence | 1-5 / 10 000 | 46.01 / 100 000 | Europe | Value and class | Validated | 22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER] |
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/842
- This record as JSON: /data/d/842.json