{"orpha":842,"name":"Testicular seminomatous germ cell tumor","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Seminoma of testis","Seminomatous germ cell tumor of testis","Testicular seminoma"],"definition":"Testicular seminomatous germ cell tumor is a rare testicular germ cell tumor, most commonly presenting with a painless mass in the scrotum, with a very high cure rate if caught in the early stages.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-842/","orphanet_url":"https://www.orpha.net/en/disease/detail/842","names":{"fr":{"name":"Tumeur testiculaire germinale séminomateuse","synonyms":["Séminome des testicules","Séminome testiculaire","Tumeur germinale séminomateuse des testicules"],"definition":"La tumeur testiculaire germinale séminomateuse est une tumeur germinale des testicules rare se manifestant le plus souvent par une masse indolore au niveau du scrotum, et possédant un taux très élevé de guérison s'il est traité précocement."},"de":{"name":"Testikulärer Keimzelltumor, seminomatöser","synonyms":["Seminom des Hodens","Seminom, testikuläres","Seminomatöser Keimzelltumor des Hodens"]},"es":{"name":"Tumor testicular de células germinales seminomatoso","synonyms":["Seminoma de los testículos","Seminoma testicular","Tumor de células germinales seminomatoso de los testículos"],"definition":"Es un tumor testicular de células germinales poco frecuente que se suele presentar como una masa indolora en el escroto, con una tasa de curación muy alta si se detecta en las primeras etapas."},"it":{"name":"Tumore testicolare seminomatoso delle cellule germinali","synonyms":["Seminoma del testicolo","Seminoma testicolare","Tumore seminomatoso delle cellule germinali del testicolo"]},"nl":{"name":"Testiculaire seminomateuze kiemceltumor","synonyms":["Seminomateuze kiemceltumor van de testis","Seminoom van de testis","Testiculair seminoom"],"definition":"Testiculaire seminomateuze kiemceltumor is een zeldzame testiculaire kiemceltumor (zie deze term), die doorgaans tot uiting komt als een pijnloos gezwel in het scrotum en een hoge genezingsgraad heeft indien detectie in de vroege stadia gebeurt."},"pt":{"name":"Seminoma testicular","synonyms":["Disgerminoma"]},"pl":{"name":"Nasieniak","synonyms":["Nasieniak jąder"]},"cs":{"name":"Testikulární seminomatózní nádor ze zárodečných buněk","synonyms":["Seminom varlete","Testikulární seminom","Seminomatózní nádor varlete ze zárodečných buněk"]},"uk":{"name":"Семіноматозна герміногенна пухлина яєчка","synonyms":["Семінома яєчка","Семіноматозна герміногенна пухлина яєчка","Семінома яєчка"],"definition":"Testicular seminomatous germ cell tumor is a rare testicular germ cell tumor (see this term), most commonly presenting with a painless mass in the scrotum, with a very high cure rate if caught in the early stages."},"zh":{"name":"睾丸精原细胞瘤","synonyms":["睾丸精原细胞性生殖细胞肿瘤"]},"tr":{"name":"Testis seminomatöz germ hücreli tümör","synonyms":["Testis seminomu","Testis seminomu","Testisin seminomatöz germ hücreli tümörü"]}},"xrefs":[{"source":"OMIM","code":"273300","qualifier":"NTBT","icd_relation":null,"validated":true},{"source":"ICD-10","code":"C62.9","qualifier":"NTBT","icd_relation":"index","validated":true},{"source":"ICD-11","code":"2C80.2","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1731624064"},{"source":"MONDO","code":"0003669","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5551428","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"4792","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10062124","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":99864,"name":"OBSOLETE: Classic seminoma","status":"inactive"}],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":363504,"name":"Germ cell tumor of testis","classifications":[185,202,233]}],"children":[],"genes":[{"symbol":"KIT","name":"KIT proto-oncogene, receptor tyrosine kinase","gene_type":"gene with protein product","association":"Disease-causing somatic mutation(s) in","status":"Assessed","source":"14695343[PMID]","hgnc":"6342","ensembl":"ENSG00000157404","omim":"164920","loci":["4q12"]}],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.71,"area":"Europe","status":"Validated","source":"22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Lifetime Prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":46.01,"area":"Europe","status":"Validated","source":"22033323[PMID]_RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}