raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:83311

Rocky Mountain spotted fever

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare, acquired, life-threatening, infectious disease due to the tick-borne bacteria <i>Rickettsia rickettsii</i> characterized by an acute onset of fever, malaise, and severe headache, variably accompanied by myalgia, anorexia, nausea, vomiting, abdominal pain, and photophobia, associating (2-5 days after fever onset) a typically erythematous, blanching or non-blanching, maculopapluar rash with petechiae, starting on the wrists and ankles and progressing centrifugally to the palms and soles and centripetally to the arms, legs and trunk. Additonal variable features may include conjunctivitis, mucosal ulcers, post-inflammatory hyperpigmentation, jaundice, pneumonia, hepatomegaly, renal failure, meningismus, amnesia, optic disc edema, and ocular arterial occlusion.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enRocky Mountain spotted fever
frFièvre pourprée des Montagnes Rocheuses
deRocky-Mountain-Fleckfieber
esFiebre maculosa de las Montañas Rocosas
itFebbre maculosa delle Montagne Rocciose
nlRocky Mountain-vlekkenkoorts
ptFebre maculosa das Montanhas Rochosas
plGorączka plamista z Gór Skalistych
csHorečka Skalistých hor
ukПлямиста лихоманка Скелястих гір
zh落矶山斑疹热
trKayalık Dağlar benekli humması

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10A77.0Especificvalidated
ICD-111C31.0Especificvalidated
MONDO0019359Evalidated
MeSHD012373Evalidated
UMLSC0035793Evalidated
GARD7585Evalidated
MedDRA10039207Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

2 records
TypeClassValueAreaQualificationValidationSource
Annual incidence1-9 / 1 000 0000.24 / 100 000United StatesValue and classNot yet validatedORPHANET
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

7

Sources for this card