raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:810

Shigellosis

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare bacterial infectious disease characterized by dysentery caused by Shigella. There are four species (S. dysenteriae, S. flexneri, S. boydii and S. sonnei), all of which cause bacillary dysentery and are strictly limited to human hosts. Affected individuals present with dysenteric syndrome with 10-30 glairy, bloody and watery stools per day, a high temperature (40°C), abdominal pain/cramps and tenesmus following an incubation period of 2-3 days.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enShigellosis
frShigellose
deShigellose
esShigelosis
itShighellosi
nlShigellose
ptShigelose
plSzigelloza
csShigelóza
ukШигельоз
zh细菌性痢疾
trŞigelloz

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10A03.0BTNTspecificvalidated
ICD-10A03.1BTNTspecificvalidated
ICD-10A03.2BTNTspecificvalidated
ICD-10A03.3BTNTspecificvalidated
ICD-10A03.8BTNTspecificvalidated
ICD-10A03.9BTNTspecificvalidated
ICD-111A02Especificvalidated
MONDO0019345Evalidated
UMLSC0013371Evalidated
GARD4818Evalidated
MedDRA10054178Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

30 records
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET
Annual incidence1-9 / 100 0001.68 / 100 000EuropeValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0008.18 / 100 000BulgariaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.33 / 100 000CroatiaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2015[OTHER]
Annual incidence<1 / 1 000 0000.04 / 100 000CyprusValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0001.6 / 100 000Czech RepublicValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0002.08 / 100 000DenmarkValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0001.38 / 100 000EstoniaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0001.82 / 100 000FinlandValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.78 / 100 000AustriaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0002.54 / 100 000FranceValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.7 / 100 000GermanyValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.74 / 100 000GreeceValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.38 / 100 000HungaryValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0001.12 / 100 000IrelandValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.34 / 100 000LatviaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0001.12 / 100 000LithuaniaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0002.6 / 100 000LuxembourgValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.34 / 100 000MaltaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0002.4 / 100 000NetherlandsValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence<1 / 1 000 0000.02 / 100 000PolandValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence<1 / 1 000 0000.08 / 100 000PortugalValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0001.18 / 100 000RomaniaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0006.1 / 100 000SlovakiaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0001.02 / 100 000SloveniaValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.44 / 100 000SpainValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0003.68 / 100 000SwedenValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0003.32 / 100 000United KingdomValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.3 / 100 000IcelandValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 100 0002.06 / 100 000NorwayValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

46 annotations · validated 2020-04-02
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0032155Abdominal cramps
HP:0002027Abdominal pain
HP:0025086Bloody mucoid diarrhea
HP:0001945Fever
Frequent (79-30%)
HP:0003111Abnormal blood ion concentration
HP:0002039Anorexia
HP:0025406Asthenia
HP:0001944Dehydration
HP:0012378Fatigue
HP:0001974Increased total leukocyte count
HP:0002018Nausea
HP:0012702Tenesmus
HP:0002013Vomiting
Occasional (29-5%)
HP:0025615Abscess
HP:0100282Acute colitis
HP:0025085Bloody diarrhea
HP:0001531Failure to thrive in infancy
HP:0002373Febrile seizure (within the age range of 3 months to 6 years)
HP:0001943Hypoglycemia
HP:0002902Hyponatremia
HP:0031274Hypovolemic shock
HP:0002721Immunodeficiency
HP:0002590Paralytic ileus
HP:0100279Ulcerative colitis
Very rare (<4-1%)
HP:0001919Acute kidney injury
HP:0001369Arthritis
HP:0031864Bacteremia
HP:0001396Cholestasis
HP:0000509Conjunctivitis
HP:0012804Corneal ulceration
HP:0005575Hemolytic-uremic syndrome
HP:0001399Hepatic failure
HP:0031368Intestinal perforation
HP:0001937Microangiopathic hemolytic anemia
HP:0012819Myocarditis
HP:0009830Peripheral neuropathy
HP:0002586Peritonitis
HP:0002090Pneumonia
HP:0000979Purpura
HP:0003201Rhabdomyolysis
HP:0100806Sepsis
HP:0025059Splenic abscess
HP:0001873Thrombocytopenia
HP:0500006Urethritis
HP:0001025Urticaria
HP:0000554Uveitis

Run the differential on the 4 obligate / very frequent terms

Annotation source: 27556171[PMID]_24891600[PMID]_17399943[PMID]

7

Sources for this card