ORPHA:781
Q fever
Synonyms: Coxiellosis · Infection due to Coxiella burnetii · Nine Mile fever · Quadrilateral fever · Query fever
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Q fever, caused by <i>Coxiella burnetii</i>, is a bacterial zoonosis with a wide clinical spectrum that can be life-threatening and, in some cases, can become chronic.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Q fever | Coxiellosis · Infection due to Coxiella burnetii · Nine Mile fever · Quadrilateral fever · Query fever |
| fr | Fièvre Q | Coxiellose · Fièvre du Montana · Fièvre quadrilatérale · Infection à Coxiella burnetii |
| de | Q-Fieber | Coxiellose · Infektion durch Coxiella burnetii · Query-Fieber · Schlachthausfieber · Siebentagefieber |
| es | Fiebre Q | Coxielosis · Fiebre 'query' · Fiebre cuadrilateral · Fiebre de Nine Mile · Infección por Coxiella burnetii |
| it | Febbre Q | Coxiellosi · Febbre Query · Febbre di Nine Mile · Febbre quadrilaterale · Infezione da Coxiella burnetii |
| nl | Q-koorts | Coxiellose · Infectie door Coxiella burnetii · Nine Mile koorts · Quadrilaterale koorts · Querykoorts |
| pt | Febre Q | |
| pl | Gorączka Q | Koksielloza · Zakażenie Coxiella burnetii |
| cs | Horečka Q | Koxielóza · Infekce způsobená Coxiellou burnetii · Horečka Nine Mile · Horečka Quadrilateral |
| uk | Q лихоманка | Коксієльоз · Інфекція, спричинена Coxiella burnetii · Лихоманка Девятої милі · Чотирикутна лихоманка · Лихоманка Квері |
| zh | Q热 | 贝氏柯克斯体所致感染 |
| tr | Q ateşi | Coxiellosis · Query ateşi · Nine Mile ateşi · Kuadrilateral ateş · Koksiella burnetii'ye bağlı enfeksiyon |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A78 | E | specific | validated |
| ICD-11 | DB98.3 | E | specific | validated |
| MONDO | 0019186 | E | validated | |
| MeSH | D011778 | E | validated | |
| UMLS | C0034362 | E | validated | |
| GARD | 7515 | E | validated | |
| MedDRA | 10037688 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163582Rare bacterial infectious disease
rare infectious diseases
No children.
4
Genes
0 directOrphanet records no gene directly on this code.
5
Prevalence and incidence
24 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | 0.03 / 100 000 | United States | Value and class | Validated | 23535757[PMID]_Center for Diseases Control and Prevention[OTHER] |
| Annual incidence | 1-9 / 100 000 | 3 / 100 000 | Australia | Value and class | Validated | 16503466[PMID] |
| Annual incidence | 1-9 / 1 000 000 | 0.16 / 100 000 | Europe | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Point prevalence | Unknown | — | Europe | Class only | Not yet validated | ORPHANET |
| Annual incidence | <1 / 1 000 000 | 0.08 / 100 000 | Belgium | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.26 / 100 000 | Bulgaria | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.4 / 100 000 | Croatia | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.32 / 100 000 | Cyprus | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | <1 / 1 000 000 | 0.04 / 100 000 | Finland | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.26 / 100 000 | France | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.26 / 100 000 | Germany | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.1 / 100 000 | Greece | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.64 / 100 000 | Hungary | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | <1 / 1 000 000 | 0.06 / 100 000 | Ireland | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | <1 / 1 000 000 | 0.07 / 100 000 | Latvia | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | <1 / 1 000 000 | 0.04 / 100 000 | Luxembourg | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.1 / 100 000 | Malta | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.18 / 100 000 | Netherlands | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.2 / 100 000 | Portugal | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.1 / 100 000 | Romania | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.1 / 100 000 | Slovenia | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | <1 / 1 000 000 | — | Sweden | Class only | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.1 / 100 000 | United Kingdom | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
| Annual incidence | <1 / 1 000 000 | 0.05 / 100 000 | Norway | Value and class | Validated | European Centre for Disease prevention and Control 2012-2016[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
6
HPO phenotypes
62 annotations · validated 2024-06-17| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0032252 | Granuloma | |
| Frequent (79-30%) | ||
| HP:0002014 | Diarrhea | |
| HP:0002910 | Elevated circulating hepatic transaminase concentration | |
| HP:0003565 | Elevated erythrocyte sedimentation rate | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| HP:0002315 | Headache | |
| HP:0001324 | Muscle weakness | |
| HP:0003326 | Myalgia | |
| HP:0002017 | Nausea and vomiting | |
| HP:0000613 | Photophobia | |
| HP:0000988 | Skin rash | |
| HP:0001744 | Splenomegaly | |
| Occasional (29-5%) | ||
| HP:0001626 | Abnormality of the cardiovascular system | |
| HP:0001392 | Abnormality of the liver | |
| HP:0001903 | Anemia | |
| HP:0002039 | Anorexia | |
| HP:0020136 | Anticardiolipin IgG antibody positivity | |
| HP:0003613 | Antiphospholipid antibody positivity | |
| HP:0002829 | Arthralgia | |
| HP:0012735 | Cough | |
| HP:0000716 | Depression | |
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| HP:0100584 | Endocarditis | |
| HP:0000790 | Hematuria | |
| HP:0001878 | Hemolytic anemia | |
| HP:0012115 | Hepatitis | |
| HP:0002240 | Hepatomegaly | |
| HP:0001433 | Hepatosplenomegaly | |
| HP:0002922 | Increased CSF protein concentration | |
| HP:0010702 | Increased circulating immunoglobulin concentration | |
| HP:0001511 | Intrauterine growth retardation | |
| HP:0000952 | Jaundice | |
| HP:0040186 | Maculopapular exanthema | |
| HP:0030166 | Night sweats | |
| HP:0033430 | Non-infectious meningitis | |
| HP:0001562 | Oligohydramnios | |
| HP:0002090 | Pneumonia | |
| HP:0001622 | Premature birth | |
| HP:0000979 | Purpura | |
| HP:0002923 | Rheumatoid factor positive | |
| HP:0002360 | Sleep abnormality | |
| HP:0001518 | Small for gestational age | |
| HP:0003262 | Smooth muscle antibody positivity | |
| HP:0001873 | Thrombocytopenia | |
| HP:0002633 | Vasculitis | |
| HP:0001824 | Weight loss | |
| Very rare (<4-1%) | ||
| HP:0005162 | Abnormal left ventricular function | |
| HP:0006530 | Abnormal pulmonary interstitial morphology | |
| HP:0011034 | Amyloidosis | |
| HP:0001082 | Cholecystitis | |
| HP:0100778 | Cryoglobulinemia | |
| HP:0002383 | Infectious encephalitis | |
| HP:0025343 | Lupus anticoagulant | |
| HP:0002716 | Lymphadenopathy | |
| HP:0001287 | Meningitis | |
| HP:0012819 | Myocarditis | |
| HP:0002754 | Osteomyelitis | |
| HP:0001698 | Pericardial effusion | |
| HP:0001701 | Pericarditis | |
| HP:0002202 | Pleural effusion | |
| HP:0002098 | Respiratory distress | |
Run the differential on the 1 obligate / very frequent terms
Annotation source: 32629489[PMID]_32310555[PMID]_18755387[PMID]_22226692[PMID]
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/781
- This record as JSON: /data/d/781.json