Angiostrongyliasis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A foodborne zoonotic disease, endemic to Southeast Asia and the Pacific Islands, caused by the rat lungworm <i>Angiostrongylus cantonensis</i> and that is acquired by the ingestion of the infective larvae on vegetables or in raw or undercooked snails, slugs, land crabs, freshwater shrimps, frogs and lizards. The main feature is eosinophilic meningitis, with clinical manifestations including fever, headache, malaise, fatigue, vomiting, rhinorrhea, blurred vision, diplopia, cough, stiff neck, enteritis, constipation and paraesthesia due to the movement of the worms from the intestines to the lungs, central nervous system and eyes. In severe cases without treatment, coma and death can occur.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Angiostrongyliasis | |
| fr | Angiostrongylose | |
| de | Angiostrongylose | Angiostrongyliasis |
| es | Angiostrongilosis | |
| it | Angiostrongilosi | |
| nl | Angiostrongyliasis | |
| pt | Angiostrongiliose | |
| pl | Angiostrogyloza | |
| cs | Angiostrongyliasis | |
| uk | Ангіостронгіліаз | |
| zh | 血管圆线虫病 | |
| tr | Anjiyostrongiloz |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | B81.3 | BTNT | specific | validated |
| ICD-10 | B83.2 | BTNT | specific | validated |
| ICD-11 | 1F60 | E | specific | validated |
| ICD-11 | 1F60.0 | BTNT | specific | validated |
| ICD-11 | 1F60.1 | BTNT | specific | validated |
| ICD-11 | 1F60.Y | BTNT | attributed | validated |
| MONDO | 0019143 | E | validated | |
| MeSH | C536369 | E | validated | |
| UMLS | C0392662 | E | validated | |
| GARD | 683 | E | validated | |
| MedDRA | 10069517 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163588Rare parasitic disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
39 annotations · validated 2020-04-14| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0012229 | CSF pleocytosis | |
| HP:0002315 | Headache | |
| HP:0032061 | Hypereosinophilia | |
| Frequent (79-30%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0002829 | Arthralgia | |
| HP:0410263 | Brain imaging abnormality | |
| HP:0002019 | Constipation | |
| HP:0000651 | Diplopia | |
| HP:0001262 | Excessive daytime somnolence | |
| HP:0012378 | Fatigue | |
| HP:0001945 | Fever | |
| HP:0032064 | Gastrointestinal eosinophilia | |
| HP:0002516 | Increased intracranial pressure | |
| HP:0000737 | Irritability | |
| HP:0001287 | Meningitis | |
| HP:0003326 | Myalgia | |
| HP:0003401 | Paresthesia | |
| HP:0004396 | Poor appetite | |
| HP:0002587 | Projectile vomiting | |
| HP:0025258 | Stiff neck | |
| HP:0011450 | Unusual CNS infection | |
| HP:0002013 | Vomiting | |
| Occasional (29-5%) | ||
| HP:0000622 | Blurred vision | |
| HP:0002181 | Cerebral edema | |
| HP:0002460 | Distal muscle weakness | |
| HP:0003261 | Increased circulating IgA level | |
| HP:0003237 | Increased circulating IgG level | |
| HP:0003496 | Increased circulating IgM level | |
| HP:0032336 | Increased circulating specific IgE antibody | |
| HP:0001324 | Muscle weakness | |
| HP:0002018 | Nausea | |
| HP:0030833 | Neck pain | |
| HP:0031179 | Nuchal rigidity | |
| HP:0012531 | Pain | |
| HP:0000989 | Pruritus | |
| HP:0001250 | Seizure | |
| HP:0002119 | Ventriculomegaly | |
| Very rare (<4-1%) | ||
| HP:0001259 | Coma | |
| HP:0100963 | Hyperesthesia | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 29411969[PMID]_18922484[PMID]_31287041[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/74
- This record as JSON: /data/d/74.json