raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:730396

Invasive meningococcal disease

Synonyms: IMD

Type
Disease
Group
Disorder
Inheritance
Not applicable
Status
active

Orphadata ships no English definition for this code.

1

Names in Orphadata languages

9 of 12 languages
LangNameSynonyms
enInvasive meningococcal diseaseIMD
frInfection invasive à méningocoqueIIM
deInvasive Meningokokkenerkrankung= en
esEnfermedad meningocócica invasivaEMI
itMalattia meningococcica invasiva= en
nlInvasieve meningokokkenziekteInvasieve infectie door Neisseria meningitidis · IMD · Invasieve meningokokkeninfectie
ptInvasive meningococcal disease
plInvasive meningococcal disease= en
csInvasive meningococcal disease= en
2

Cross-references

qualifier = Orphanet mapping relation

No cross-references in this release.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

Codes that Orphanet moved or referred to this one:

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

0 records

No prevalence record in this release.

6

HPO phenotypes

34 annotations · validated 2020-02-07
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0012229CSF pleocytosis
HP:0001945Fever
HP:0011972Hypoglycorrhachia
HP:0002922Increased CSF protein concentration
HP:0031179Nuchal rigidity
HP:0025258Stiff neck
Frequent (79-30%)
HP:0002039Anorexia
HP:0011227Elevated circulating C-reactive protein concentration
HP:0002315Headache
HP:0000967Petechiae
HP:0000613Photophobia
HP:0002587Projectile vomiting
HP:0004372Reduced consciousness
HP:0100806Sepsis
HP:0000988Skin rash
Occasional (29-5%)
HP:6000647Bulging fontanelle
HP:0002329Drowsiness
HP:0000365Hearing impairment
HP:0002615Hypotension
HP:0032308Increased circulating procalcitonin concentration
HP:0002516Increased intracranial pressure
HP:0000737Irritability
HP:0001254Lethargy
HP:0001085Papilledema
HP:0003401Paresthesia
HP:0000979Purpura
HP:0000083Renal insufficiency
HP:0001250Seizure
Very rare (<4-1%)
HP:0011880Acute disseminated intravascular coagulation
HP:0006824Cranial nerve paralysis
HP:0002045Hypothermia
HP:0002643Neonatal respiratory distress
HP:0031273Shock
HP:0001297Stroke

Run the differential on the 6 obligate / very frequent terms

Annotation source: 30860561[PMID]_31990941[PMID]_31956973[PMID]_29203096[PMID]

7

Sources for this card