ORPHA:70475
Radiation proctitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult
- Status
- active
Radiation proctitis is a rare rectal disease directly induced by pelvic radiotherapy and characterized by rectal bleeding, change in bowel habits, tenesmus and sepsis.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Radiation proctitis | |
| fr | Proctite radique | |
| de | Radiogene Proktitis | Strahlenproktitis |
| es | Proctitis por radiación | |
| it | Proctite da radiazioni | |
| nl | Radiatieproctitis | Bestralingsproctitis · Proctitis door straling |
| pt | Proctite por radiação | |
| pl | Popromienne zapalenie prostnicy | |
| cs | Radiační proktitida | |
| uk | Променевий проктит | |
| zh | 放射性直肠炎 | |
| tr | Radyasyon proktit |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | K62.7 | E | specific | validated |
| ICD-11 | DB33.42 | E | specific | validated |
| MONDO | 0019084 | E | validated | |
| UMLS | C0400827 | E | validated | |
| MedDRA | 10037766 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:521132Radiation-induced disorder
rare disorders due to toxic effects - ORPHA:117569Rare intestinal disease
rare gastroenterological diseases
No children.
4
Genes
0 directOrphanet records no gene directly on this code.
5
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 35 / 100 000 | Europe | Value and class | Validated | European Medicines Agency[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
6
HPO phenotypes
19 annotations · validated 2023-08-17| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0025015 | Abnormal vascular morphology | |
| HP:0003549 | Abnormality of connective tissue | |
| HP:0004296 | Abnormality of gastrointestinal vasculature | |
| HP:0002034 | Abnormality of the rectum | |
| HP:0002597 | Abnormality of the vasculature | |
| HP:0002583 | Colitis | |
| HP:0005224 | Rectal abscess | |
| HP:0100590 | Rectal fistula | |
| Frequent (79-30%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0500005 | Anal pain | |
| HP:0002019 | Constipation | |
| HP:0100279 | Ulcerative colitis | |
| Occasional (29-5%) | ||
| HP:0012089 | Arteritis | |
| HP:0005214 | Intestinal obstruction | |
| HP:0100806 | Sepsis | |
| HP:0012702 | Tenesmus | |
| Very rare (<4-1%) | ||
| HP:0002607 | Bowel incontinence | |
| HP:0002014 | Diarrhea | |
| HP:0002573 | Hematochezia | |
Run the differential on the 8 obligate / very frequent terms
Annotation source: 27504391[PMID]_36660465[PMID]
7
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/70475
- This record as JSON: /data/d/70475.json