ORPHA:700
Alopecia totalis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Multigenic/multifactorial
- Age of onset
- All ages
- Status
- active
A form of alopecia areata, an inflammatory disease of the hair follicle, characterized by a complete loss of hair of the entire scalp which becomes glabrous.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Alopecia totalis | |
| fr | Pelade totale | |
| de | Alopecia totalis | |
| es | Alopecia total | |
| it | Alopecia areata totale | |
| nl | Alopecia totalis | |
| pt | Alopecia totalis | |
| pl | Łysienie całkowite | |
| cs | Alopecia totalis | |
| uk | Тотальна алопеція | |
| zh | 全秃 | |
| tr | Alopesi totalis |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| OMIM | 104000 | NTBT | validated | |
| OMIM | 300042 | BTNT | validated | |
| OMIM | 610753 | BTNT | validated | |
| ICD-10 | L63.0 | E | specific | validated |
| ICD-11 | ED70.21 | E | specific | validated |
| MONDO | 0019080 | E | validated | |
| UMLS | C0263504 | E | validated | |
| GARD | 1470 | E | validated | |
| MedDRA | 10001766 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:79364Alopecia
rare skin diseases
No children.
4
Genes
0 directOrphanet records no gene directly on this code.
5
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 10.5 / 100 000 | Europe | Value and class | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
6
HPO phenotypes
10 annotations · validated 2023-09-18| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0002293 | Alopecia of scalp | |
| HP:0007418 | Alopecia totalis | |
| Occasional (29-5%) | ||
| HP:0002960 | Autoimmunity | |
| HP:0001808 | Fragile nails | |
| HP:0002037 | Inflammation of the large intestine | |
| HP:0001803 | Nail pits | |
| HP:0001806 | Onycholysis | |
| HP:0030804 | Trachyonychia | |
| HP:0100651 | Type I diabetes mellitus | |
| HP:0001045 | Vitiligo | |
Run the differential on the 2 obligate / very frequent terms
Annotation source: 33085372[PMID]
7
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/700
- This record as JSON: /data/d/700.json