raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:685082

Pediatric acute respiratory distress syndrome

Synonyms: PARDS · Pediatric ARDS

Type
Disease
Group
Disorder
Inheritance
Multigenic/multifactorial
Status
active

Orphadata ships no English definition for this code.

1

Names in Orphadata languages

9 of 12 languages
LangNameSynonyms
enPediatric acute respiratory distress syndromePARDS · Pediatric ARDS
frSyndrome de détresse respiratoire aiguë de l'enfantSDRA de l'enfant
deAkutes pädiatrisches AtemnotsyndromARDS im Kindesalter · Akutes nicht obstruktives Lungenversagen im Kindesalter · PARDS · Pädiatrisches ARDS
esSíndrome de dificultad respiratoria aguda pediátricaPARDS · SDRA pediátrico
itSindrome pediatrica da distress respiratorio acutoPARDS · PARDS pediatrica
nlPediatrisch acuut ademhalingsnoodsyndroomPARDS · Pediatrisch ARDS · Pediatrisch acute respiratory distress-syndroom
ptSíndrome pediátrico de dificuldade respiratória agudaARDS pediátrico · PARDS
plPediatric acute respiratory distress syndrome= en
csSyndrom akutní dechové tísně u dětí= en
2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-11CB00NTBTattributedvalidated
MONDO100131Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

Codes that Orphanet moved or referred to this one:

4

Genes

3 direct
GeneAssociationStatusHGNCEnsemblOMIMLocusNameSource of validation
ABCA3Candidate gene tested inNot yet assessedHGNC:33ENSG0000016797260161516p13.3ATP binding cassette subfamily A member 327516224[PMID]
SFTPBMajor susceptibility factor inAssessedHGNC:10801ENSG000001688781786402p11.2surfactant protein B11063734[PMID]
SFTPCMajor susceptibility factor inAssessedHGNC:10802ENSG000001684841786208p21.3surfactant protein C29805340[PMID]
5

Prevalence and incidence

0 records

No prevalence record in this release.

6

HPO phenotypes

16 annotations · validated 2020-03-18
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0012418Hypoxemia
Frequent (79-30%)
HP:0000765Abnormal thorax morphology
HP:0100750Atelectasis
HP:0000961Cyanosis
HP:0030863Nasal flaring
HP:0001622Premature birth
HP:0100598Pulmonary edema
HP:0002878Respiratory failure
HP:0002789Tachypnea
Occasional (29-5%)
HP:0001662Bradycardia
HP:0001695Cardiac arrest
HP:0002615Hypotension
HP:0002090Pneumonia
HP:0011947Respiratory tract infection
HP:0001649Tachycardia
Very rare (<4-1%)
HP:0100806Sepsis

Run the differential on the 1 obligate / very frequent terms

Annotation source: 10762543[PMID]_28589372[PMID]_30379667[PMID]

7

Sources for this card