ORPHA:673
Malaria
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A life-threatening parasitic disease caused by <i>Plasmodium</i> (<i>P. </i>) parasites that are transmitted by <i>Anophles</i> mosquito bites to humans and is typically clinically characterized by attacks of fever, headache, chills and vomiting.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Malaria | |
| fr | Paludisme | Malaria |
| de | Malaria | |
| es | Malaria | Paludismo |
| it | Malaria | |
| nl | Malaria | |
| pt | Malária | |
| pl | Malaria | |
| cs | Malárie | |
| uk | Малярія | |
| zh | 疟疾 | |
| tr | Sıtma |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| OMIM | 611162 | E | validated | |
| ICD-10 | B50.0 | BTNT | specific | validated |
| ICD-10 | B50.8 | BTNT | specific | validated |
| ICD-10 | B50.9 | BTNT | specific | validated |
| ICD-10 | B51.0 | BTNT | specific | validated |
| ICD-10 | B51.8 | BTNT | specific | validated |
| ICD-10 | B51.9 | BTNT | specific | validated |
| ICD-10 | B52.0 | BTNT | specific | validated |
| ICD-10 | B52.8 | BTNT | specific | validated |
| ICD-10 | B52.9 | BTNT | specific | validated |
| ICD-10 | B53.0 | BTNT | specific | validated |
| ICD-10 | B53.1 | BTNT | specific | validated |
| ICD-10 | B53.8 | BTNT | specific | validated |
| ICD-10 | B54 | BTNT | specific | validated |
| ICD-11 | 1F40 | BTNT | specific | validated |
| ICD-11 | 1F41 | BTNT | specific | validated |
| ICD-11 | 1F42 | BTNT | specific | validated |
| ICD-11 | 1F43 | BTNT | specific | validated |
| ICD-11 | 1F44 | BTNT | specific | validated |
| ICD-11 | 1F45 | BTNT | specific | validated |
| MONDO | 0005136 | E | validated | |
| MeSH | D008288 | E | validated | |
| UMLS | C0024530 | E | validated | |
| GARD | 6961 | E | validated | |
| MedDRA | 10025487 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163588Rare parasitic disease
rare infectious diseases
No children.
4
Genes
0 directOrphanet records no gene directly on this code.
5
Prevalence and incidence
31 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 3 / 100 000 | Europe | Value and class | Validated | European Medicines Agency2015[OTHER] |
| Annual incidence | 1-5 / 10 000 | 12 / 100 000 | France | Value and class | Not yet validated | ORPHANET |
| Annual incidence | 6-9 / 10 000 | 73 / 100 000 | Worldwide | Value and class | Not yet validated | ORPHANET |
| Annual incidence | 1-9 / 100 000 | 1.2 / 100 000 | Europe | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.8 / 100 000 | Austria | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 2.1 / 100 000 | Belgium | Value and class | Validated | European Centre for Disease prevention and Control 2011-2015[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.16 / 100 000 | Bulgaria | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.1 / 100 000 | Croatia | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.52 / 100 000 | Cyprus | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.32 / 100 000 | Czech Republic | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.2 / 100 000 | Estonia | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.74 / 100 000 | Finland | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.68 / 100 000 | Greece | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.14 / 100 000 | Hungary | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.7 / 100 000 | Ireland | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.18 / 100 000 | Latvia | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.22 / 100 000 | Lithuania | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.84 / 100 000 | Luxembourg | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.54 / 100 000 | Malta | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.84 / 100 000 | Netherlands | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | <1 / 1 000 000 | 0.08 / 100 000 | Poland | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.44 / 100 000 | Portugal | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.16 / 100 000 | Romania | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | <1 / 1 000 000 | 0.06 / 100 000 | Slovakia | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.28 / 100 000 | Slovenia | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.5 / 100 000 | Spain | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.88 / 100 000 | Sweden | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 2.38 / 100 000 | United Kingdom | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.62 / 100 000 | Norway | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 100 000 | 1.62 / 100 000 | Denmark | Value and class | Validated | European Centre for Disease prevention and Control 2013-2017[OTHER] |
| Annual incidence | 1-9 / 1 000 000 | 0.75 / 100 000 | Iceland | Value and class | Validated | European Centre for Disease prevention and Control 2016-2017[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
6
HPO phenotypes
16 annotations · validated 2017-01-25| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001919 | Acute kidney injury | |
| HP:0001903 | Anemia | |
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| HP:0001945 | Fever | |
| HP:0002315 | Headache | |
| HP:0002011 | Morphological central nervous system abnormality | |
| HP:0002017 | Nausea and vomiting | |
| Frequent (79-30%) | ||
| HP:0001871 | Abnormality of blood and blood-forming tissues | |
| HP:0100543 | Cognitive impairment | |
| HP:0002141 | Gait imbalance | |
| HP:0002904 | Hyperbilirubinemia | |
| HP:0003326 | Myalgia | |
| HP:0004372 | Reduced consciousness | |
| HP:0002098 | Respiratory distress | |
| HP:0001873 | Thrombocytopenia | |
| Occasional (29-5%) | ||
| HP:0000488 | Retinopathy | |
Run the differential on the 7 obligate / very frequent terms
Annotation source: 27175507[PMID]
7
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/673
- This record as JSON: /data/d/673.json