raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:658917

Clonorchiasis

Type
Disease
Group
Disorder
Inheritance
Not applicable
Status
active

A rare parasitic disease characterized by infection with the trematode <i>Clonorchis sinensis</i> (Chinese or oriental liver fluke) through ingestion of metacercarial cysts via infected raw or undercooked fish. Clinical symptoms are related to worm burden. Most acute infections are asymptomatic or present with mild abdominal symptoms. Patients with high worm burdens experience fever, headache, right upper-quadrant abdominal pain, and intermittent colic pain caused by the worms obstructing the gallbladder. Chronic infections are usually severe, resulting in fibrosis of small bile ducts and destruction of the adjacent liver parenchyma, and strongly associated with cholangiocarcinoma.

1

Names in Orphadata languages

10 of 12 languages
LangNameSynonyms
enClonorchiasis
frClonorchiase
deClonorchiasisChinesischer oder orientalischer Leberegel-Infektion
esClonorquiasis
itClonorchiasi
nlClonorchiasisChinese leverbotziekte
ptClonorquíase
plKlonorchoza
csKlonorchióza
ukКлонорхоз

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10B66.1Especificvalidated
ICD-111F80Especificvalidated
MONDO0005705Evalidated
MONDO5705Evalidated
UMLSC0009021Evalidated
MedDRA10009344Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

0 records

No prevalence record in this release.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

7

Sources for this card