Borna virus encephalitis
Synonyms: Bornavirus encephalitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adolescent, Adult, Elderly
- Status
- active
A rare infectious disease characterized by severe non-purulent meningoencephalitis caused by Borna disease virus 1 (BoDV-1). Patients present with fever, headache, malaise, and fatigue, followed after a few days by nausea, confusion and disorientation, and psychomotor slowing. Ataxia, aphasia, dyspnea, multifocal myoclonic jerks, and paraplegia have been described. The condition is very often fatal after progress to lethargy, deteriorating brain stem reflexes, and coma. Examination of the cerebrospinal fluid reveals moderate lympho-monocytic pleocytosis and presence of BoDV-1 RNA.
Names in Orphadata languages
10 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Borna virus encephalitis | Bornavirus encephalitis |
| fr | Encéphalite à virus Borna | |
| de | Borna-Virus-Enzephalitis | |
| es | Encefalitis por virus Borna | Encefalitis por Bornavirus |
| it | Encefalite da virus Borna | Encefalite da Bornavirus |
| nl | Encefalitis door bornavirus | Borna-virus-encefalitis |
| pt | Encefalite Borna virus | Encefalite por Bornavirus |
| pl | Zapalenie mózgu wywołane wirusem Borna | = en |
| cs | Bornavirová encefalitida | = en |
| uk | Борнавірусний енцефаліт | Борнавірусний енцефаліт |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A85.8 | NTBT | attributed | validated |
| ICD-11 | 1C80 | NTBT | index | validated |
| MONDO | 0957421 | E | validated | |
| UMLS | C5816783 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:166490Infectious disease with epilepsy
rare neurological diseases - ORPHA:98252Infectious encephalitis
rare neurological diseases; rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 18 cases | Worldwide | Case(s) | Validated | 31924550[PMID] | |
| Point prevalence | <1 / 1 000 000 | — | Worldwide | Class only | Validated | 31924550[PMID]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/637051
- This record as JSON: /data/d/637051.json