Postinfectious cerebellitis
Synonyms: ACA · APCA · Acute cerebellar ataxia · Acute postinfectious cerebellar ataxia · PIC · Para-infectious cerebellitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare cerebellar ataxia characterized by cerebellar inflammation caused by viral or bacterial infection-triggered, immune-mediated mechanisms. It mainly affects young children following an episode of usually viral infection (notably varicella), but sometimes also adults, mostly upon Epstein-Barr virus or mycoplasma infection. Affected individuals mainly present with acute-onset afebrile gait ataxia, meningeal signs, high intracranial pressure with or without extracerebellar manifestations (such as clouding of consciousness, seizures and altered mental status) or extracerebellar focal signs. Mild behavioral changes can also be present. Pleocytosis in cerebrospinal fluid is reported in the majority of the patients.
Names in Orphadata languages
10 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Postinfectious cerebellitis | ACA · APCA · Acute cerebellar ataxia · Acute postinfectious cerebellar ataxia · PIC · Para-infectious cerebellitis |
| fr | Cérébellite post-infectieuse | ACA · Ataxie cérébelleuse aiguë · Ataxie cérébelleuse aiguë post-infectieuse · Cérébellite para-infectieuse |
| de | Postinfektiöse Zerebellitis | Akute postinfektiöse zerebelläre Ataxie · Akute zerebelläre Ataxie · PIC · Parainfektiöse Zerebellitis · ACA · APCA |
| es | Cerebelitis posinfecciosa | Ataxia cerebelosa aguda · Ataxia cerebelosa aguda postinfecciosa · Cerebelitis parainfecciosa |
| it | Cerebellite post-infettiva | ACA · ACAP · Atassia cerebellare acuta · Atassia cerebellare acuta post-infettiva · CPI · Cerebellite para-infettiva |
| nl | Postinfectieuze cerebellitis | ACA · APCA · Acute cerebellaire ataxie · Acute postinfectieuze cerebellaire ataxie · PIC · Parainfectieuze cerebellitis |
| pt | Cerebelite pós-infeciosa | ACA · APCA · Ataxia cerebelosa aguda · Ataxia cerebelosa pós-infeciosa aguda · Cerebelite para-infeciosa · PIC |
| pl | Poinfekcyjne zapalenie móżdżku | = en |
| cs | Postinfekční cerebelitida | = en |
| uk | Постінфекційний церебелліт | ACA · Гостра мозочкова атаксія · Гостра постінфекційна мозочкова атаксія · APCA · Параінфекційний церебелліт · PIC |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G04.8 | NTBT | attributed | validated |
| MONDO | 0850107 | E | validated | |
| UMLS | C5575321 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:623638Immune-mediated cerebellar ataxia
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | 31515702[PMID]_ORPHANET |
| Annual incidence | Unknown | — | Worldwide | Class only | Validated | 31515702[PMID]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/624244
- This record as JSON: /data/d/624244.json