Chronic intervillositis of unknown etiology
Synonyms: CIUE
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adolescent, Adult
- Status
- active
A rare disorder related to pregnancy characterized by a placental inflammatory process with clusters of histiocytes and associated fibrin in intervillous spaces, resulting in adverse pregnancy outcomes including intrauterine growth restriction, preterm birth, and pregnancy loss. Higher grading according to the proportion of involved intervillous space has been associated with poorer outcomes. There is a significant risk of recurrence in subsequent pregnancies.
Names in Orphadata languages
10 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Chronic intervillositis of unknown etiology | CIUE |
| fr | Intervillite chronique d'étiologie indéterminée | ICEI · Intervillite chronique sans étiologie connue |
| de | Chronische Intervillositis unbekannter Ätiologie | = en |
| es | Intervillositis crónica de etiología desconocida | |
| it | Intervillosite cronica a eziologia ignota | = en |
| nl | Chronische intervillositis met onbekende etiologie | = en |
| pt | Intervilosite crónica de etiologia desconhecida | = en |
| pl | Przewlekłe zapalenie międzykosmków o nieznanej etiologii | = en |
| cs | Chronická intervilozitida neznámé etiologie | = en |
| uk | Хронічний інтервілозит невідомої етіології | = en |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | O43.8 | NTBT | attributed | validated |
| ICD-11 | JA86.4 | NTBT | attributed | validated |
| MONDO | 0035882 | E | validated | |
| UMLS | C5680386 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163637Rare disorder related with pregnancy, childbirth and puerperium
rare gynecological and obstetric diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | 32841927[PMID]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/615970
- This record as JSON: /data/d/615970.json