Argyria
Synonyms: Silver staining
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare dermatosis, which can be either localized or generalized, that occurs after prolonged contact and absorption of silver containing compounds over a period of years and that is characterized by irreversible blue-gray to gray-black staining of skin, fingernails and/or mucous membranes, most evident on sun exposed areas of the skin. Silver exposure is usually occupational but may also occur through dental amalgams, the ingestion of colloidal silver, acupuncture needles, orthopedic implants and topical medications (such as silver sulfadiazine).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Argyria | Silver staining |
| fr | Argyrie | Imprégnation cutanéo-muqueuse à l'argent |
| de | Argyrie | |
| es | Argiria | Tinción de plata · Tinción por exposición a plata |
| it | Argiria | Colorazione argento |
| nl | Argyrie | Zilverkleuring |
| pt | Argiria | Coloração pela prata |
| pl | Srebrzyca | = en |
| cs | Argyrie | Šedavé zbarvení kůže |
| uk | Аргірія | Фарбування сріблом |
| zh | 银质沉着病 | 银染色 |
| tr | Arjiri | Gümüş boyama |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | T56.8 | NTBT | index | validated |
| ICD-11 | ED6Y | NTBT | index | validated |
| MONDO | 0018952 | E | validated | |
| MeSH | D001129 | E | validated | |
| UMLS | C0003782 | E | validated | |
| MedDRA | 10003094 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:556508Rare disorder due to poisoning
rare disorders due to toxic effects
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/60014
- This record as JSON: /data/d/60014.json