ORPHA:585956
B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)
Synonyms: B lymphoblastic leukemia lymphoma with t(1;19)(q23;p13.3); TCF3-PBX1
- Type
- Etiological subtype
- Group
- Subtype of disorder
- Inheritance
- Not applicable
- Age of onset
- Adolescent, Adult, Childhood
- Status
- active
Orphadata ships no English definition for this code.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) | B lymphoblastic leukemia lymphoma with t(1;19)(q23;p13.3); TCF3-PBX1 |
| fr | Leucémie/lymphome lymphoblastique B associé à t(1;19)(q23;p13.3) | Leucémie/lymphome lymphoblastique B avec t(1;19)(q23;p13.3); TCF3-PBX1 |
| de | B-lymphoblastische Leukämie/Lymphom mit t(1;19)(q23;p13.3) | B-lymphoblastische Leukämie/Lymphom mit t(1;19)(q23;p13.3); TCF3-PBX1 |
| es | Leucemia/linfoma linfoblástico B con t(1;19)(q23;p13.3) | Leucemia/linfoma linfoblástico de células B con t(1;19)(q23;p13.3); TCF3-PBX1 |
| it | Leucemia linfoblastica a cellule B/linfoma con t(1;19)(q23;p13.3) | Leucemia linfoblastica a cellule B/linfoma con t(1;19)(q23;p13.3); TCF3-PBX1 |
| nl | B-lymfoblastische leukemie/lymfoom met t(1;19)(q23;p13.3) | B-lymfoblastische leukemie/lymfoom met t(1;19)(q23;p13.3); TCF3-PBX1 |
| pt | Leucemia/linfoma linfoblástico-B com t(1;19)(q23;p13.3) | |
| pl | Białaczka/chłoniak limfoblastyczny z komórek B z t(1;19)(q23;p13.3) | Białaczka/chłoniak limfoblastyczny z komórek B z t(1;19)(q23;p13.3); TCF3-PBX1 |
| cs | B-lymfoblastická leukémie/lymfom s t(1;19)(q23;p13.3) | = en |
| uk | В-лімфобластний лейкоз/лімфома з t(1;19)(q23;p13.3) | Лімфобластний лейкоз В, лімфома з t(1;19)(q23;p13.3); TCF3-PBX1 |
| zh | B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) | = en |
| tr | B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3) | = en |
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | C91.0 | NTBT | attributed | validated |
| ICD-11 | 2A70.Y | NTBT | index | validated |
| ICD-11 | XH3GU8 | E | specific | validated |
| MONDO | 0600030 | E | validated | |
| UMLS | C2698315 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:99860Precursor B-cell acute lymphoblastic leukemia
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders
No children.
4
Genes
2 direct| Gene | Association | Status | HGNC | Ensembl | OMIM | Locus | Name | Source of validation |
|---|---|---|---|---|---|---|---|---|
| PBX1 | Part of a fusion gene in | Assessed | HGNC:8632 | ENSG00000185630 | 176310 | 1q23.3 | PBX homeobox 1 | 31575852[PMID] |
| TCF3 | Part of a fusion gene in | Assessed | HGNC:11633 | ENSG00000071564 | 147141 | 19p13.3 | transcription factor 3 | 31575852[PMID] |
5
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | Unknown | — | Worldwide | Class only | Validated | WHO Classification of Tumours[OTHER]_ORPHANET |
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | WHO Classification of Tumours[OTHER]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/585956
- This record as JSON: /data/d/585956.json