ORPHA:585936
B-lymphoblastic leukemia/lymphoma with hyperdiploidy
- Type
- Etiological subtype
- Group
- Subtype of disorder
- Inheritance
- Not applicable
- Age of onset
- Adolescent, Adult, Childhood
- Status
- active
Orphadata ships no English definition for this code.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | B-lymphoblastic leukemia/lymphoma with hyperdiploidy | |
| fr | Leucémie/lymphome lymphoblastique B avec hyperdiploïdie | |
| de | B-lymphoblastische Leukämie/Lymphom mit Hyperdiploidie | |
| es | Leucemia/linfoma linfoblástico de células B con hiperdiploidía | |
| it | Leucemia linfoblastica a cellule B/linfoma con iperdiploidia | |
| nl | B-lymfoblastische leukemie/lymfoom met hyperdiploïdie | |
| pt | Leucemia/linfoma linfoblástico-B com hiperdiploidia | |
| pl | Białaczka/chłoniak limfoblastyczny z komórek B z hiperdiploidią | |
| cs | B-lymfoblastická leukémie/lymfom s hyperdiploidií | |
| uk | В-лімфобластний лейкоз/лімфома з гіпердіплоїдією | |
| zh | B-lymphoblastic leukemia/lymphoma with hyperdiploidy | |
| tr | B-lymphoblastic leukemia/lymphoma with hyperdiploidy |
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | C91.0 | NTBT | attributed | validated |
| ICD-11 | 2A70.Y | NTBT | index | validated |
| MONDO | 0035943 | E | validated | |
| UMLS | C2698311 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
3
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:99860Precursor B-cell acute lymphoblastic leukemia
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders
No children.
4
Genes
2 direct| Gene | Association | Status | HGNC | Ensembl | OMIM | Locus | Name | Source of validation |
|---|---|---|---|---|---|---|---|---|
| GATA3 | Major susceptibility factor in | Assessed | HGNC:4172 | ENSG00000107485 | 131320 | 10p14 | GATA binding protein 3 | 23996088[PMID]_24141364[PMID]_24203929[PMID] |
| PIP4K2A | Major susceptibility factor in | Assessed | HGNC:8997 | ENSG00000150867 | 603140 | 10p12.2 | phosphatidylinositol-5-phosphate 4-kinase type 2 alpha | 23996088[PMID] |
5
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | Unknown | — | Worldwide | Class only | Validated | WHO Classification of Tumours[OTHER]_ORPHANET |
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | WHO Classification of Tumours[OTHER]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
6
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/585936
- This record as JSON: /data/d/585936.json