ORPHA:585929

B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)

Synonyms: B lymphoblastic leukemia lymphoma with t(12;21)(p13;q22); TEL-AML1 · B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1

Type: Etiological subtype
Group: Subtype of disorder
Inheritance: Not applicable
Age of onset: Adolescent, Adult, Childhood
Status: active

Orphadata ships no English definition for this code.

Names in Orphadata languages

12 of 12 languages

Lang	Name	Synonyms
en	B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)	B lymphoblastic leukemia lymphoma with t(12;21)(p13;q22); TEL-AML1 · B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1
fr	Leucémie/lymphome lymphoblastique B associé à t(12;21)(p13.2;q22.1)	Leucémie/lymphome lymphoblastique B avec t(12;21)(p13.2;q22.1); ETV6-RUNX1 · Leucémie/lymphome lymphoblastique B avec t(12;21)(p13.2;q22.1); TEL-AML1
de	B-lymphoblastische Leukämie/Lymphom mit t(12;21)(p13.2;q22.1)	B-lymphoblastische Leukämie/Lymphom mit t(12;21)(p13.2;q22.1); ETV6-RUNX1 · B-lymphoblastische Leukämie/Lymphom mit t(12;21)(p13;q22); TEL-AML1
es	Leucemia/linfoma linfoblástico de células B con t(12;21)(p13.2;q22.1)	Leucemia/linfoma linfoblástico de células B con t(12;21)(p13.2;q22.1); ETV6-RUNX1 · Leucemia/linfoma linfoblástico de células B con t(12;21)(p13;q22); TEL-AML1
it	Leucemia linfoblastica a cellule B/linfoma con t(12;21)(p13.2;q22.1)	Leucemia linfoblastica a cellule B/linfoma con t(12;21)(p13.2;q22.1); ETV6-RUNX1 · Leucemia linfoblastica a cellule B/linfoma con t(12;21)(p13;q22); TEL-AML1
nl	B-lymfoblastische leukemie/lymfoom met t(12;21)(p13.2;q22.1)	B-lymfoblastische leukemie/lymfoom met t(12;21)(p13.2;q22.1); ETV6-RUNX1 · B-lymfoblastische leukemie/lymfoom met t(12;21)(p13;q22); TEL-AML1
pt	Leucemia/linfoma linfoblástico-B com t(12;21)(p13.2;q22.1)
pl	Białaczka/chłoniak limfoblastyczny z komórek B z t(12;21)(p13.2;q22.1)	Białaczka/chłoniak limfoblastyczny z komórek B z t(12;21)(p13;q22); TEL-AML1 · Białaczka/chłoniak limfoblastyczny z komórek B z t(12;21)(p13;q22); ETV6-RUNX1
cs	B-lymfoblastická leukémie/lymfom s t(12;21)(p13.2;q22.1)	= en
uk	В-лімфобластний лейкоз/лімфома з t(12;21)(p13.2;q22.1)	Лімфобластний лейкоз В, лімфома з t(12;21)(p13;q22); TEL-AML1 · В-лімфобластний лейкоз/лімфома з t(12;21)(p13.2;q22.1); ETV6-RUNX1
zh	B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)	= en
tr	B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)	= en

Cross-references

qualifier = Orphanet mapping relation

Source	Code	Qualifier	ICD relation	Validation
ICD-10	C91.0	NTBT	attributed	validated
ICD-11	2A70.Y	NTBT	index	validated
ICD-11	XH4KA2	E	specific	validated
MONDO	0035942	E		validated
UMLS	C2698314	E		validated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

Classification

Preferential parent (Orphanet linearisation):

ORPHA:250908Rare neoplastic disease

Parents in the classifications (1):

ORPHA:99860Precursor B-cell acute lymphoblastic leukemia
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders

No children.

Genes

1 direct

Gene	Association	Status	HGNC	Ensembl	OMIM	Locus	Name	Source of validation
ETV6	Part of a fusion gene in	Assessed	HGNC:3495	ENSG00000139083	600618	12p13.2	ETS variant transcription factor 6	23491079[PMID]

Prevalence and incidence

2 records

Type	Class	Value	Area	Qualification	Validation	Source
Annual incidence	Unknown	—	Worldwide	Class only	Validated	WHO Classification of Tumours[OTHER]_ORPHANET
Point prevalence	Unknown	—	Worldwide	Class only	Validated	WHO Classification of Tumours[OTHER]_ORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

Sources for this card

Orphanet page: orpha.net/en/disease/detail/585929
This record as JSON: /data/d/585929.json