{"orpha":585929,"name":"B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)","type":"Etiological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["B lymphoblastic leukemia lymphoma with t(12;21)(p13;q22); TEL-AML1","B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1"],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-585929/","orphanet_url":"https://www.orpha.net/en/disease/detail/585929","names":{"fr":{"name":"Leucémie/lymphome lymphoblastique B associé à t(12;21)(p13.2;q22.1)","synonyms":["Leucémie/lymphome lymphoblastique B avec t(12;21)(p13.2;q22.1); ETV6-RUNX1","Leucémie/lymphome lymphoblastique B avec t(12;21)(p13.2;q22.1); TEL-AML1"]},"de":{"name":"B-lymphoblastische Leukämie/Lymphom mit t(12;21)(p13.2;q22.1)","synonyms":["B-lymphoblastische Leukämie/Lymphom mit t(12;21)(p13.2;q22.1); ETV6-RUNX1","B-lymphoblastische Leukämie/Lymphom mit t(12;21)(p13;q22); TEL-AML1"]},"es":{"name":"Leucemia/linfoma linfoblástico de células B con t(12;21)(p13.2;q22.1)","synonyms":["Leucemia/linfoma linfoblástico de células B con t(12;21)(p13.2;q22.1); ETV6-RUNX1","Leucemia/linfoma linfoblástico de células B con t(12;21)(p13;q22); TEL-AML1"]},"it":{"name":"Leucemia linfoblastica a cellule B/linfoma con t(12;21)(p13.2;q22.1)","synonyms":["Leucemia linfoblastica a cellule B/linfoma con t(12;21)(p13.2;q22.1); ETV6-RUNX1","Leucemia linfoblastica a cellule B/linfoma con t(12;21)(p13;q22); TEL-AML1"]},"nl":{"name":"B-lymfoblastische leukemie/lymfoom met t(12;21)(p13.2;q22.1)","synonyms":["B-lymfoblastische leukemie/lymfoom met t(12;21)(p13.2;q22.1); ETV6-RUNX1","B-lymfoblastische leukemie/lymfoom met t(12;21)(p13;q22); TEL-AML1"]},"pt":{"name":"Leucemia/linfoma linfoblástico-B com t(12;21)(p13.2;q22.1)"},"pl":{"name":"Białaczka/chłoniak limfoblastyczny z komórek B z t(12;21)(p13.2;q22.1)","synonyms":["Białaczka/chłoniak limfoblastyczny z komórek B z t(12;21)(p13;q22); TEL-AML1","Białaczka/chłoniak limfoblastyczny z komórek B z t(12;21)(p13;q22); ETV6-RUNX1"]},"cs":{"name":"B-lymfoblastická leukémie/lymfom s t(12;21)(p13.2;q22.1)","synonyms":["B lymphoblastic leukemia lymphoma with t(12;21)(p13;q22); TEL-AML1","B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1"]},"uk":{"name":"В-лімфобластний лейкоз/лімфома з t(12;21)(p13.2;q22.1)","synonyms":["Лімфобластний лейкоз В, лімфома з t(12;21)(p13;q22); TEL-AML1","В-лімфобластний лейкоз/лімфома з t(12;21)(p13.2;q22.1); ETV6-RUNX1"]},"zh":{"name":"B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)","synonyms":["B lymphoblastic leukemia lymphoma with t(12;21)(p13;q22); TEL-AML1","B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1"]},"tr":{"name":"B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)","synonyms":["B lymphoblastic leukemia lymphoma with t(12;21)(p13;q22); TEL-AML1","B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1"]}},"xrefs":[{"source":"ICD-10","code":"C91.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2A70.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"988256163"},{"source":"ICD-11","code":"XH4KA2","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"323964002"},{"source":"MONDO","code":"0035942","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C2698314","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":99860,"name":"Precursor B-cell acute lymphoblastic leukemia","classifications":[194,202,233]}],"children":[],"genes":[{"symbol":"ETV6","name":"ETS variant transcription factor 6","gene_type":"gene with protein product","association":"Part of a fusion gene in","status":"Assessed","source":"23491079[PMID]","hgnc":"3495","ensembl":"ENSG00000139083","omim":"600618","loci":["12p13.2"]}],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Adult","Childhood"],"prevalence":[{"type":"Annual incidence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"WHO Classification of Tumours[OTHER]_ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"WHO Classification of Tumours[OTHER]_ORPHANET"}],"phenotypes":null}