ORPHA:585918
B-lymphoblastic leukemia/lymphoma with t(v;11q23.3)
Synonyms: B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged · B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged
- Type
- Etiological subtype
- Group
- Subtype of disorder
- Inheritance
- Not applicable
- Age of onset
- Adolescent, Adult, Childhood, Infancy
- Status
- active
Orphadata ships no English definition for this code.
1
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) | B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged · B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged |
| fr | Leucémie/lymphome lymphoblastique B associé à t(v;11q23.3) | Leucémie/lymphome lymphoblastique B avec t(v;11q23.3) · Lymphome/leucémie lymphoblastique à cellules B avec t(v;11q23); MLL réarrangé |
| de | B-lymphoblastische Leukämie/Lymphom mit t(v;11q23.3) | B-lymphoblastische Leukämie/Lymphom mit t(v;11q23); MLL-Rearrangement · B-lymphoblastische Leukämie/Lymphom mit t(v;11q23.3); KMT2A-Rearrangement |
| es | Leucemia/linfoma linfoblástico de células B con t(v;11q23.3) | Leucemia/linfoma linfoblástico de células B con t(v;11q23); reordenamiento del gen MLL · Leucemia/linfoma linfoblástico de células B con t(v;11q23.3); reordenamiento del gen KMT2A |
| it | Leucemia linfoblastica a cellule B/linfoma con t(v;11q23.3) | Leucemia linfoblastica a cellule B/linfoma con t(v;11q23.3); con riarrangiamenti in KMT2A · Leucemia linfoblastica a cellule B/linfoma con t(v;11q23.3); con riarrangiamenti in MLL |
| nl | B-lymfoblastische leukemie/lymfoom met t(v;11q23.3) | B-lymfoblastische leukemie/lymfoom met t(v;11q23); MLL herschikt · B-lymfoblastische leukemie/lymfoom met t(v;11q23.3); KMT2A herschikt |
| pt | Leucemia/linfoma linfoblástico-B com t(v;11q23.3) | |
| pl | Białaczka/chłoniak limfoblastyczny z komórek B z t(v;11q23.3) | Białaczka/chłoniak limfoblastyczny z komórek B z t(v;11q23.3); z rearanżacjami MLL · Białaczka/chłoniak limfoblastyczny z komórek B z t(v;11q23.3); z rearanżacjami KMT2A |
| cs | B-lymfoblastická leukémie/lymfom s t(v;11q23.3) | = en |
| uk | В-лімфобластний лейкоз/лімфома з t(v;11q23.3) | В лімфобластний лейкоз лімфома з t(v;11q23); MLL реаранжування · B Лімфобластний лейкоз/лімфома з t(v;11q23.3); KMT2A реаранжування |
| zh | B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) | = en |
| tr | B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) | = en |
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | C91.0 | NTBT | attributed | validated |
| ICD-11 | 2A70.Y | NTBT | index | validated |
| ICD-11 | XH8GG0 | E | specific | validated |
| MONDO | 0035941 | E | validated | |
| UMLS | C2698309 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:99860Precursor B-cell acute lymphoblastic leukemia
rare hematological diseases; rare neoplastic diseases; rare transplant-related disorders
No children.
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Genes
1 direct| Gene | Association | Status | HGNC | Ensembl | OMIM | Locus | Name | Source of validation |
|---|---|---|---|---|---|---|---|---|
| KMT2A | Part of a fusion gene in | Assessed | HGNC:7132 | ENSG00000118058 | 159555 | 11q23.3 | lysine methyltransferase 2A | 30487223[PMID] |
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Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | Unknown | — | Worldwide | Class only | Validated | WHO Classification of Tumours[OTHER]_ORPHANET |
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | WHO Classification of Tumours[OTHER]_ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/585918
- This record as JSON: /data/d/585918.json