{"orpha":585918,"name":"B-lymphoblastic leukemia/lymphoma with t(v;11q23.3)","type":"Etiological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged","B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged"],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-585918/","orphanet_url":"https://www.orpha.net/en/disease/detail/585918","names":{"fr":{"name":"Leucémie/lymphome lymphoblastique B associé à t(v;11q23.3)","synonyms":["Leucémie/lymphome lymphoblastique B avec t(v;11q23.3)","Lymphome/leucémie lymphoblastique à cellules B avec t(v;11q23); MLL réarrangé"]},"de":{"name":"B-lymphoblastische Leukämie/Lymphom mit t(v;11q23.3)","synonyms":["B-lymphoblastische Leukämie/Lymphom mit t(v;11q23); MLL-Rearrangement","B-lymphoblastische Leukämie/Lymphom mit t(v;11q23.3); KMT2A-Rearrangement"]},"es":{"name":"Leucemia/linfoma linfoblástico de células B con t(v;11q23.3)","synonyms":["Leucemia/linfoma linfoblástico de células B con t(v;11q23); reordenamiento del gen MLL","Leucemia/linfoma linfoblástico de células B con t(v;11q23.3); reordenamiento del gen KMT2A"]},"it":{"name":"Leucemia linfoblastica a cellule B/linfoma con t(v;11q23.3)","synonyms":["Leucemia linfoblastica a cellule B/linfoma con t(v;11q23.3); con riarrangiamenti in KMT2A","Leucemia linfoblastica a cellule B/linfoma con t(v;11q23.3); con riarrangiamenti in MLL"]},"nl":{"name":"B-lymfoblastische leukemie/lymfoom met t(v;11q23.3)","synonyms":["B-lymfoblastische leukemie/lymfoom met t(v;11q23); MLL herschikt","B-lymfoblastische leukemie/lymfoom met t(v;11q23.3); KMT2A herschikt"]},"pt":{"name":"Leucemia/linfoma linfoblástico-B com t(v;11q23.3)"},"pl":{"name":"Białaczka/chłoniak limfoblastyczny z komórek B z t(v;11q23.3)","synonyms":["Białaczka/chłoniak limfoblastyczny z komórek B z t(v;11q23.3); z rearanżacjami MLL","Białaczka/chłoniak limfoblastyczny z komórek B z t(v;11q23.3); z rearanżacjami KMT2A"]},"cs":{"name":"B-lymfoblastická leukémie/lymfom s t(v;11q23.3)","synonyms":["B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged","B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged"]},"uk":{"name":"В-лімфобластний лейкоз/лімфома з t(v;11q23.3)","synonyms":["В лімфобластний лейкоз лімфома з t(v;11q23); MLL реаранжування","B Лімфобластний лейкоз/лімфома з t(v;11q23.3); KMT2A реаранжування"]},"zh":{"name":"B-lymphoblastic leukemia/lymphoma with t(v;11q23.3)","synonyms":["B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged","B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged"]},"tr":{"name":"B-lymphoblastic leukemia/lymphoma with t(v;11q23.3)","synonyms":["B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged","B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged"]}},"xrefs":[{"source":"ICD-10","code":"C91.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2A70.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"225752797"},{"source":"ICD-11","code":"XH8GG0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"923510880"},{"source":"MONDO","code":"0035941","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C2698309","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":99860,"name":"Precursor B-cell acute lymphoblastic leukemia","classifications":[194,202,233]}],"children":[],"genes":[{"symbol":"KMT2A","name":"lysine methyltransferase 2A","gene_type":"gene with protein product","association":"Part of a fusion gene in","status":"Assessed","source":"30487223[PMID]","hgnc":"7132","ensembl":"ENSG00000118058","omim":"159555","loci":["11q23.3"]}],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Adult","Childhood","Infancy"],"prevalence":[{"type":"Annual incidence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"WHO Classification of Tumours[OTHER]_ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"WHO Classification of Tumours[OTHER]_ORPHANET"}],"phenotypes":null}