raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:576074

Middle East respiratory syndrome

Synonyms: MERS

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare infectious disease caused by Middle East respiratory syndrome coronavirus (MERS‐CoV) and characterized by a spectrum of illness, ranging from mild upper respiratory symptoms to rapidly progressive lower respiratory infection/pneumonia potentially leading to acute respiratory distress syndrome (ARDS), multi-system organ failure, and death. Presenting signs and symptoms typically include fever, cough, shortness of breath, chills, dyspnea, myalgia, abdominal pain, nausea, vomiting, and diarrhea.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enMiddle East respiratory syndromeMERS
frSyndrome respiratoire du Moyen-Orient= en
deMittlerer-Osten-Atemwegssyndrom= en
esSíndrome respiratorio de Oriente Medio= en
itSindrome respiratoria del Medio Oriente= en
nlMidden-Oosten respiratoir syndroom= en
ptSíndrome Respiratório do Médio Oriente= en
plZespół oddechowy na Bliskim Wschodzie= en
csRespirační syndrom na Středním východě= en
ukБлизькосхідний респіраторний синдром= en
zh中东呼吸综合征= en
trOrta Doğu solunum sendromu= en

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10B34.2NTBTattributedvalidated
ICD-111D64Especificvalidated
MONDO0100116Evalidated
MeSHD065207Evalidated
UMLSC3694279Evalidated
MedDRA10075271Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (2):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

2 records
TypeClassValueAreaQualificationValidationSource
Cases/families2613 casesWorldwideCase(s)ValidatedWorld Health Organization 2024[OTHER]
Point prevalence<1 / 1 000 000—WorldwideClass onlyValidatedWorld Health Organization 2024[OTHER]_ORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

Orphanet has no HPO annotation for this code in this release.

7

Sources for this card