SUNCT syndrome
Synonyms: Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adult
- Status
- active
A rare primary headache disorder characterized by unilateral trigeminal pain that occurs in association with ipsilateral cranial autonomic symptoms (conjunctival injection and tearing).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | SUNCT syndrome | Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing |
| fr | Céphalée névralgique unilatérale brève avec injection conjonctivale | Syndrome SUNCT |
| de | SUNCT-Syndrom | Kurz anhaltender einseitiger neuralgiformer Kopf- und Gesichtsschmerz mit konjunktivaler Injektion und Gesichtschwitzen |
| es | Síndrome SUNCT | Cefalea unilateral neuralgiforme de breve duración con reacción conjuntival y lagrimeo |
| it | Sindrome SUNCT | Cefalea con attacchi nevralgiformi monolaterali di breve durata con iniezione congiuntivale e lacrimazione |
| nl | SUNCT-syndroom | Kortdurende unilaterale neuralgiforme aanvallen van hoofdpijn met conjunctivale injectie en traanvorming |
| pt | Síndrome SUNCT | Cefaleia neuralgiforme unilateral de curta-duração com hiperémia conjuntival e lacrimejo |
| pl | Zespół SUNCT | Krótkotrwały jednostronny ból głowy przypominający neuralgię z towarzyszącym przekrwieniem spojówek i łzawieniem |
| cs | SUNCT syndrom | Krátce trvající jednostranné neuralgiformní bolesti hlavy s konjunktivální injekcí a slzením |
| uk | Синдром SUNCT | Короткочасні односторонні напади невралгічного головного болю з інєкцією та сльозотечею конюнктиви |
| zh | SUNCT综合征 | 单侧短暂性神经头痛伴球结膜充血和流泪 |
| tr | SUNCT sendromu | Konjonktival enjeksiyon ve yırtılma ile seyreden kısa süreli unilateral nevraljiform baş ağrısı atakları |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G44.8 | NTBT | attributed | validated |
| ICD-11 | 8A82 | NTBT | index | validated |
| MONDO | 0018927 | E | validated | |
| MeSH | D050798 | E | validated | |
| UMLS | C1262087 | E | validated | |
| GARD | 9257 | E | validated | |
| MedDRA | 10061981 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:157843Trigeminal autonomic cephalalgia
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 6.7 / 100 000 | Europe | Value and class | Validated | [EXPERT] |
| Point prevalence | 1-9 / 100 000 | 6.7 / 100 000 | Australia | Value and class | Validated | 18325769[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
23 annotations · validated 2020-02-11| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0030953 | Conjunctival hyperemia | |
| HP:0009926 | Epiphora | |
| HP:0032148 | Episodic pain | |
| Frequent (79-30%) | ||
| HP:0000713 | Agitation | |
| HP:0001069 | Episodic hyperhidrosis | |
| HP:0031284 | Flushing | |
| HP:0000975 | Hyperhidrosis | |
| HP:0031731 | Increased tear production | |
| HP:0002076 | Migraine | |
| HP:0000508 | Ptosis | |
| HP:0000711 | Restlessness | |
| HP:0031417 | Rhinorrhea | |
| HP:0100661 | Trigeminal neuralgia | |
| Occasional (29-5%) | ||
| HP:0030766 | Ear pain | |
| HP:0000282 | Facial edema | |
| HP:0001041 | Facial erythema | |
| HP:0040264 | Jaw pain | |
| HP:0000616 | Miosis | |
| HP:0001742 | Nasal congestion | |
| HP:0002018 | Nausea | |
| HP:0100540 | Palpebral edema | |
| HP:0000613 | Photophobia | |
| Very rare (<4-1%) | ||
| HP:0002013 | Vomiting | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 29931416[PMID]_31427501[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/57145
- This record as JSON: /data/d/57145.json