{"orpha":57145,"name":"SUNCT syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing"],"definition":"A rare primary headache disorder characterized by unilateral trigeminal pain that occurs in association with ipsilateral cranial autonomic symptoms (conjunctival injection and tearing).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-57145/","orphanet_url":"https://www.orpha.net/en/disease/detail/57145","names":{"fr":{"name":"Céphalée névralgique unilatérale brève avec injection conjonctivale","synonyms":["Syndrome SUNCT"],"definition":"Céphalée primaire rare caractérisée par une douleur unilatérale du trijumeau associée à des troubles autonomes crâniens ipsilatéraux (injection conjonctivale et larmoiement)."},"de":{"name":"SUNCT-Syndrom","synonyms":["Kurz anhaltender einseitiger neuralgiformer Kopf- und Gesichtsschmerz mit konjunktivaler Injektion und Gesichtschwitzen"],"definition":"Eine seltene primäre Kopfschmerzerkrankung, die durch einen einseitigen Trigeminusschmerz gekennzeichnet ist, der in Verbindung mit ipsilateralen kranialen autonomen Symptomen (Bindehautinjektion und Tränenfluss) auftritt."},"es":{"name":"Síndrome SUNCT","synonyms":["Cefalea unilateral neuralgiforme de breve duración con reacción conjuntival y lagrimeo"],"definition":"Es una cefalea primaria poco frecuente caracterizada por dolor unilateral del trigémino asociado a síntomas autonómicos craneales ipsilaterales (inyección conjuntival y lagrimeo)."},"it":{"name":"Sindrome SUNCT","synonyms":["Cefalea con attacchi nevralgiformi monolaterali di breve durata con iniezione congiuntivale e lacrimazione"],"definition":"Si tratta di una cefalea primitiva rara, caratterizzata da dolore trigeminale monolaterale associato a sintomi del sistema autonomo dei nervi cranici omolaterali (iniezione congiuntivale e lacrimazione)."},"nl":{"name":"SUNCT-syndroom","synonyms":["Kortdurende unilaterale neuralgiforme aanvallen van hoofdpijn met conjunctivale injectie en traanvorming"],"definition":"Een zeldzame, primaire hoofdpijnaandoening, gekenmerkt door unilaterale pijn aan nervus trigeminus die optreedt in associatie met ipsilaterale craniale autonome symptomen (hyperemie en tranenvloed van conjunctiva)."},"pt":{"name":"Síndrome SUNCT","synonyms":["Cefaleia neuralgiforme unilateral de curta-duração com hiperémia conjuntival e lacrimejo"],"definition":"A síndrome SUNCT (cefaléia de curta duração, unilateral, neuralgiforme com hiperemia conjuntival e lacrimejal) é uma cefaléia primária caracterizada por dor unilateral do trigémeo, associada a sintomas autónomos cranianos ipsilaterais (injeção conjuntival e lacrimejamento)."},"pl":{"name":"Zespół SUNCT","synonyms":["Krótkotrwały jednostronny ból głowy przypominający neuralgię z towarzyszącym przekrwieniem spojówek i łzawieniem"]},"cs":{"name":"SUNCT syndrom","synonyms":["Krátce trvající jednostranné neuralgiformní bolesti hlavy s konjunktivální injekcí a slzením"]},"uk":{"name":"Синдром SUNCT","synonyms":["Короткочасні односторонні напади невралгічного головного болю з інєкцією та сльозотечею конюнктиви"],"definition":"A rare primary headache disorder characterized by unilateral trigeminal pain that occurs in association with ipsilateral cranial autonomic symptoms (conjunctival injection and tearing)."},"zh":{"name":"SUNCT综合征","synonyms":["单侧短暂性神经头痛伴球结膜充血和流泪"]},"tr":{"name":"SUNCT sendromu","synonyms":["Konjonktival enjeksiyon ve yırtılma ile seyreden kısa süreli unilateral nevraljiform baş ağrısı atakları"]}},"xrefs":[{"source":"ICD-10","code":"G44.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"8A82","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"364704393"},{"source":"MONDO","code":"0018927","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D050798","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1262087","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"9257","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10061981","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":157843,"name":"Trigeminal autonomic cephalalgia","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":6.7,"area":"Europe","status":"Validated","source":"[EXPERT]"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":6.7,"area":"Australia","status":"Validated","source":"18325769[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2020-02-11","source":"29931416[PMID]_31427501[PMID]","terms":[{"hpo":"HP:0030953","label":"Conjunctival hyperemia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0009926","label":"Epiphora","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0032148","label":"Episodic pain","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000713","label":"Agitation","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001069","label":"Episodic hyperhidrosis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031284","label":"Flushing","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000975","label":"Hyperhidrosis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031731","label":"Increased tear production","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002076","label":"Migraine","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000508","label":"Ptosis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000711","label":"Restlessness","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031417","label":"Rhinorrhea","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100661","label":"Trigeminal neuralgia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0030766","label":"Ear pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000282","label":"Facial edema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001041","label":"Facial erythema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0040264","label":"Jaw pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000616","label":"Miosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001742","label":"Nasal congestion","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002018","label":"Nausea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100540","label":"Palpebral edema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000613","label":"Photophobia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002013","label":"Vomiting","frequency":"Very rare (<4-1%)","criteria":null}]}}