Infective endocarditis
Synonyms: Infectious endocarditis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare infectious disease characterized by inflammation of the endocardium (including native or prosthetic heart valves and indwelling cardiac devices) mainly caused by bacterial (predominantly Staphylococcus and Streptococcus species) or rarely fungal (predominantly Candida and Aspergillus species) infections that the latter are reported to be associated with high morbidity and mortality. Major clinical features include high fever or prolonged subfebrile state, chills, diaphoresis, malaise, asthenia, arthralgia, myalgia, weight loss, headache, nausea, dyspnea, cough, heart murmurs, and petechiae of the skin. The most common complications are embolism in different organs and ischemic stroke, sepsis, heart failure, and renal failure.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Infective endocarditis | Infectious endocarditis |
| fr | Endocardite infectieuse | |
| de | Endokarditis, infektiöse | |
| es | Endocarditis infecciosa | |
| it | Endocardite infettiva | Endocardite infettiva |
| nl | Infectieuze endocarditis | |
| pt | Endocardite infeciosa | |
| pl | Zapalenia wsierdzia infekcyjne | Zapalenie wsierdzia bakteryjne |
| cs | Infekční endokarditida | = en |
| uk | Інфекційний ендокардит | Бактеріальний ендокардит · Інфекційний ендокардит |
| zh | 感染性心内膜炎 | = en |
| tr | Enfektif endokardit | Bakteriyel endokardit · Enfektif endokardit |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | I33.0 | NTBT | inclusion | validated |
| ICD-11 | BB40 | E | specific | validated |
| MONDO | 0000565 | E | validated | |
| UMLS | C1541923 | E | validated | |
| GARD | 6337 | E | validated | |
| MedDRA | 10014678 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (3):
- ORPHA:163582Rare bacterial infectious disease
rare infectious diseases - ORPHA:97929Rare cardiac disease
rare cardiac diseases - ORPHA:163591Rare mycosis
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
4 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Europe | Class only | Validated | ORPHANET |
| Annual incidence | 1-9 / 100 000 | 3.38 / 100 000 | France | Value and class | Validated | 22492317[PMID] |
| Annual incidence | 1-9 / 100 000 | 1.8 / 100 000 | Denmark | Value and class | Validated | 3433553[PMID] |
| Annual incidence | 1-9 / 100 000 | — | Europe | Class only | Validated | ORPHANET_25432123[PMID] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/570762
- This record as JSON: /data/d/570762.json