ORPHA:563
Peripartum cardiomyopathy
Synonyms: Postpartum cardiomyopathy
- Type
- Disease
- Group
- Disorder
- Inheritance
- Unknown
- Age of onset
- Adult
- Status
- active
Peripartum cardiomyopathy (PPCM) is an idiopathic, potentially fatal form of dilated cardiomyopathy that develops during the final month of pregnancy or within five months after delivery.
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Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Peripartum cardiomyopathy | Postpartum cardiomyopathy |
| fr | Myocardiopathie gravidique primitive | Cardiomyopathie du péri-partum · Cardiomyopathie gravidique · Syndrome de Meadows |
| de | Kardiomyopathie, peripartale | Kardiomyopathie, postpartale · Meadows-Syndrom · PPCM · PPCMP · Peripartumkardiomyopathie |
| es | Miocardiopatía periparto | Cardiomiopatía periparto · Cardiomiopatía postparto · Síndrome de Meadow |
| it | Cardiomiopatia periparto | Cardiomiopatia postparto · Sindrome di Meadow |
| nl | Peripartumcardiomyopathie | Postpartumcardiomyopathie |
| pt | Miocardiopatia peri-parto | Miocardiopatia pós-parto |
| pl | Kardiomiopatia okołoporodowa | Kardiomiopatia poporodowa |
| cs | Peripartum kardiomyopatie | Postpartum kardiomyopatie |
| uk | Перинатальна кардіоміопатія | Післяпологова кардіоміопатія |
| zh | 围产期心肌病 | 产后心肌病 |
| tr | Peripartum kardiyomiyopatisi | Doğum sonrası kardiyomiyopati |
Definition in:
2
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | O90.3 | E | specific | validated |
| ICD-11 | JB44.3 | E | specific | validated |
| MONDO | 0018920 | E | validated | |
| UMLS | C0877208 | E | validated | |
| GARD | 220 | E | validated | |
| MedDRA | 10049430 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
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Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (3):
- ORPHA:217629Non-familial dilated cardiomyopathy
rare cardiac diseases - ORPHA:506225Rare disorder potentially indicated for heart transplant
rare transplant-related disorders - ORPHA:163637Rare disorder related with pregnancy, childbirth and puerperium
rare gynecological and obstetric diseases
No children.
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Genes
0 directOrphanet records no gene directly on this code.
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Prevalence and incidence
7 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Prevalence at birth | 1-5 / 10 000 | 30 / 100 000 | Worldwide | Value and class | Not yet validated | 10703781[PMID] |
| Prevalence at birth | 1-5 / 10 000 | 36 / 100 000 | United States | Value and class | Not yet validated | 23090517[PMID]_10703781[PMID]_16765131[PMID] |
| Prevalence at birth | 6-9 / 10 000 | 89 / 100 000 | Singapore | Value and class | Validated | 23338912[PMID] |
| Prevalence at birth | 1-9 / 100 000 | 5 / 100 000 | Japan | Value and class | Validated | 21617320[PMID] |
| Prevalence at birth | >1 / 1000 | 334 / 100 000 | Haiti | Value and class | Validated | 16342653[PMID] |
| Prevalence at birth | >1 / 1000 | 100 / 100 000 | South Africa | Value and class | Validated | 16920474[PMID] |
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
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HPO phenotypes
45 annotations · validated 2019-05-28| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0005135 | Abnormal T-wave | |
| HP:0001635 | Congestive heart failure | |
| HP:0001644 | Dilated cardiomyopathy | |
| HP:0002094 | Dyspnea | |
| HP:0030848 | Elevated jugular venous pressure | |
| HP:0002875 | Exertional dyspnea | |
| HP:0012378 | Fatigue | |
| HP:0000822 | Hypertension | |
| HP:0001712 | Left ventricular hypertrophy | |
| HP:0025169 | Left ventricular systolic dysfunction | |
| HP:0012764 | Orthopnea | |
| HP:0001962 | Palpitations | |
| HP:0010741 | Pedal edema | |
| HP:0012664 | Reduced left ventricular ejection fraction | |
| HP:0011703 | Sinus tachycardia | |
| HP:0001649 | Tachycardia | |
| Occasional (29-5%) | ||
| HP:0006705 | Abnormal atrioventricular valve morphology | |
| HP:0005120 | Abnormal cardiac atrium morphology | |
| HP:0100749 | Chest pain | |
| HP:0030830 | Crackles | |
| HP:0030148 | Heart murmur | |
| HP:0030356 | Increased serum interferon-gamma level | |
| HP:0031295 | Left atrial enlargement | |
| HP:0001653 | Mitral regurgitation | |
| HP:0012819 | Myocarditis | |
| HP:0012763 | Paroxysmal dyspnea | |
| HP:0012398 | Peripheral edema | |
| HP:0100602 | Preeclampsia | |
| HP:0002092 | Pulmonary arterial hypertension | |
| HP:0005133 | Right ventricular dilatation | |
| HP:0001708 | Right ventricular failure | |
| HP:0001907 | Thromboembolism | |
| HP:0100603 | Toxemia of pregnancy | |
| HP:0004756 | Ventricular tachycardia | |
| Very rare (<4-1%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0002926 | Abnormality of thyroid physiology | |
| HP:0001903 | Anemia | |
| HP:0002099 | Asthma | |
| HP:0002960 | Autoimmunity | |
| HP:0030149 | Cardiogenic shock | |
| HP:0000819 | Diabetes mellitus | |
| HP:0011713 | Left bundle branch block | |
| HP:0001513 | Obesity | |
| HP:0002878 | Respiratory failure | |
| HP:0002401 | Stroke-like episode | |
Annotation source: 27045128[PMID]_28765406[PMID]_25636745[PMID]
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Sources for this card
- Orphanet page: orpha.net/en/disease/detail/563
- This record as JSON: /data/d/563.json