raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:533

Listeriosis

Synonyms: Listeria infection

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A rare bacterial infectious disease caused by the foodborne pathogen <i>Listeria monocytogenes</i>, characterized by a febrile gastroenteritis, which is usually mild and self-limiting in otherwise healthy persons, but can progress to severe illness in at-risk groups like pregnant women, elderly people, immunocompromised people, and neonates. Complications include sepsis, meningitis, and encephalitis. Listeriosis during pregnancy usually occurs during the third trimester and may lead to preterm labor, miscarriage, stillbirth, or intrauterine infection of the unborn child.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enListeriosisListeria infection
frListériose
deListerioseListerien-Infektion
esListeriosisInfección por listeria
itListeriosi
nlListerioseListeria-infectie
ptListeriose
plListerioza= en
csListerióza= en
ukЛістеріозЛістеріозна інфекція
zh李斯特氏菌病李斯特菌感染
trListeriozListeria enfeksiyonu

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10A32.0BTNTspecificvalidated
ICD-10A32.1BTNTspecificvalidated
ICD-10A32.7BTNTspecificvalidated
ICD-10A32.8BTNTspecificvalidated
ICD-10A32.9BTNTspecificvalidated
ICD-111C1AEspecificvalidated
ICD-111C1A.0BTNTspecificvalidated
ICD-111C1A.1BTNTspecificvalidated
ICD-111C1A.YBTNTattributedvalidated
MONDO0005828Evalidated
MeSHD008088Evalidated
UMLSC5886852Evalidated
GARD6915Evalidated
MedDRA10024641Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

34 records
TypeClassValueAreaQualificationValidationSource
Point prevalenceUnknown—WorldwideClass onlyNot yet validatedORPHANET
Annual incidence1-9 / 1 000 0000.337 / 100 000WorldwideValue and classValidated25241232[PMID]
Annual incidence1-9 / 1 000 0000.31 / 100 000United StatesValue and classValidated17243053[PMID]_CDC Centers for disease Control and prevention 1996-2003[OTHER]
Annual incidence1-9 / 1 000 0000.43 / 100 000EuropeValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.48 / 100 000AustriaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 100 0001.07 / 100 000BelgiumValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence<1 / 1 000 0000.09 / 100 000BulgariaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence<1 / 1 000 0000.05 / 100 000CroatiaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence<1 / 1 000 0000.05 / 100 000CyprusValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.36 / 100 000Czech RepublicValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.98 / 100 000DenmarkValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.4 / 100 000EstoniaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 100 0001.1 / 100 000FinlandValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.57 / 100 000FranceValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.68 / 100 000GermanyValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.15 / 100 000GreeceValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.28 / 100 000HungaryValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.29 / 100 000PortugalValue and classValidatedEuropean Centre for Disease prevention and Control 2015-2016[OTHER]
Annual incidence<1 / 1 000 0000.05 / 100 000RomaniaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.31 / 100 000SlovakiaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.67 / 100 000SloveniaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.9 / 100 000SpainValue and classValidatedEuropean Centre for Disease prevention and Control 2011-2015[OTHER]
Annual incidence1-9 / 1 000 0000.92 / 100 000SwedenValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.3 / 100 000United KingdomValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.56 / 100 000IcelandValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.46 / 100 000NorwayValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.29 / 100 000IrelandValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.24 / 100 000ItalyValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.28 / 100 000LatviaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.25 / 100 000LithuaniaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.4 / 100 000LuxembourgValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.38 / 100 000MaltaValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.47 / 100 000NetherlandsValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]
Annual incidence1-9 / 1 000 0000.23 / 100 000PolandValue and classValidatedEuropean Centre for Disease prevention and Control 2012-2016[OTHER]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

68 annotations · validated 2020-04-03
HPOTerm (as annotated by Orphanet)Diagnostic
Very frequent (99-80%)
HP:0001945Fever
Frequent (79-30%)
HP:0010987Abnormal cellular immune system morphology
HP:0031864Bacteremia
HP:0025143Chills
HP:0012378Fatigue
HP:0002315Headache
HP:0011972Hypoglycorrhachia
HP:0002922Increased CSF protein concentration
HP:0001287Meningitis
HP:0003326Myalgia
HP:0002018Nausea
HP:0025258Stiff neck
HP:0011450Unusual CNS infection
HP:0002013Vomiting
Occasional (29-5%)
HP:0002027Abdominal pain
HP:0100022Abnormality of movement
HP:0000236Abnormality of the anterior fontanelle
HP:0025615Abscess
HP:0002829Arthralgia
HP:0001251Ataxia
HP:0003418Back pain
HP:0030049Brain abscess
HP:0006824Cranial nerve paralysis
HP:0002014Diarrhea
HP:0002955Granulomatosis
HP:0001269Hemiparesis
HP:0002721Immunodeficiency
HP:0000737Irritability
HP:0007185Loss of consciousness
HP:0001336Myoclonus
HP:0031179Nuchal rigidity
HP:0001622Premature birth
HP:0012330Pyelonephritis
HP:0002878Respiratory failure
HP:0001250Seizure
HP:0003474Somatic sensory dysfunction
HP:0005268Spontaneous abortion
HP:0001337Tremor
Very rare (<4-1%)
HP:0012747Abnormal brainstem MRI signal intensity
HP:0001919Acute kidney injury
HP:0012089Arteritis
HP:0001082Cholecystitis
HP:0001635Congestive heart failure
HP:0000509Conjunctivitis
HP:0005521Disseminated intravascular coagulation
HP:0100584Endocarditis
HP:0004302Functional motor deficit
HP:0000365Hearing impairment
HP:0011955Hepatic granulomatosis
HP:0002383Infectious encephalitis
HP:0001249Intellectual disability
HP:0007432Intermittent generalized erythematous papular rash
HP:0000952Jaundice
HP:0100523Liver abscess
HP:0012819Myocarditis
HP:0002754Osteomyelitis
HP:0001701Pericarditis
HP:0002586Peritonitis
HP:0002090Pneumonia
HP:0200039Pustule
HP:0002098Respiratory distress
HP:0003201Rhabdomyolysis
HP:0100806Sepsis
HP:0003095Septic arthritis
HP:0025059Splenic abscess
HP:0001297Stroke
HP:0032162Unusual skin infection
HP:0000572Visual loss

Run the differential on the 1 obligate / very frequent terms

Annotation source: 31837132[PMID]_25241232[PMID]_8994747[PMID]

7

Sources for this card