Cat-scratch disease
Synonyms: Bartonellosis due to Bartonella henselae infection
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
Cat-scratch disease is a rare infectious disease, caused by the Gram-negative bacteria <i>Bartonella henselae</i>, that is transmitted to humans via a scratch or bite of an infected cat and that has a variable clinical presentation but that usually manifests with an erythematous papule at the site of inoculation followed by chronic regional lymphadenopathy. Clinical course is usually self-limiting but disseminated illness with high fever, hepatosplenomegaly, granulomatous osteolytic lesions, encephalitis, retinitis, and atypical pneumonia can also occur. Cat-scratch disease can atypically present as parinaud oculoglandular syndrome (unilateral conjunctivitis and preauricular lymphadenopathy).
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Cat-scratch disease | Bartonellosis due to Bartonella henselae infection |
| fr | Maladie des griffes du chat | Bartonellose à Bartonella henselae |
| de | Katzenkratzkrankheit | Bartonellose durch Infektion mit Bartonella henselae |
| es | Enfermedad por arañazo de gato | |
| it | Malattia del graffio di gatto | Bartonellosi dovuta a infezione da Bartonella henselae |
| nl | Kattenkrabziekte | Bartonellosis als gevolg van Bartonella henselae-infectie |
| pt | Doença da arranhadela do gato | Bartonelose por infeção por Bartonella henselae |
| pl | Choroba kociego pazura | Bartonelloza spowodowana infekcją Bartonella henselae |
| cs | Nemoc z kočičího škrábnutí | Bartonellóza způsobená infekcí bakterií Bartonella henselae |
| uk | Хвороба котячих подряпин | Бартонельоз, спричинений інфекцією Bartonella henselae |
| zh | 猫抓病 | 巴尔通体属感染所致巴尔通体病 |
| tr | Kedi tırmığı hastalığı | Bartonella henselae enfeksiyonuna bağlı bartonelloz |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | A28.1 | E | specific | validated |
| ICD-11 | 1B98 | E | specific | validated |
| MONDO | 0005692 | E | validated | |
| MeSH | D002372 | E | validated | |
| UMLS | C0007361 | E | validated | |
| GARD | 27 | E | validated | |
| MedDRA | 10007729 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:163582Rare bacterial infectious disease
rare infectious diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 6.6 / 100 000 | Europe | Value and class | Validated | [EXPERT] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
22 annotations · validated 2024-07-05| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0030350 | Erythematous papule | |
| HP:0001945 | Fever | |
| HP:0002716 | Lymphadenopathy | |
| Frequent (79-30%) | ||
| HP:0002039 | Anorexia | |
| HP:0033834 | Malaise | |
| Occasional (29-5%) | ||
| HP:0002027 | Abdominal pain | |
| HP:0002829 | Arthralgia | |
| HP:0001369 | Arthritis | |
| HP:0020161 | Branch retinal artery occlusion | |
| HP:0020165 | Branch retinal vein occlusion | |
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| HP:0003565 | Elevated erythrocyte sedimentation rate | |
| HP:0001433 | Hepatosplenomegaly | |
| HP:0003326 | Myalgia | |
| HP:0100653 | Optic neuritis | |
| HP:0012121 | Panuveitis | |
| HP:0000541 | Retinal detachment | |
| HP:0032118 | Retinitis | |
| HP:0001824 | Weight loss | |
| Very rare (<4-1%) | ||
| HP:0100584 | Endocarditis | |
| HP:0033430 | Non-infectious meningitis | |
| HP:0002754 | Osteomyelitis | |
Run the differential on the 3 obligate / very frequent terms
Annotation source: 29489252[PMID]_26161064[PMID]_21243990[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/50839
- This record as JSON: /data/d/50839.json